Steven, JohnMüller, Mischa RCarvalho, Miguel FUbah, Obinna CKovaleva, MarinaDonohoe, GerardBaddeley, ThomasCornock, DawnSaunders, KennethPorter, Andrew JBarelle, Caroline Jane2017-11-152017-11-152017-10-23Steven, J, Müller, M R, Carvalho, M F, Ubah, O C, Kovaleva, M, Donohoe, G, Baddeley, T, Cornock, D, Saunders, K, Porter, A J & Barelle, C J 2017, 'In Vitro Maturation of a Humanized Shark VNAR Domain to Improve Its Biophysical Properties to Facilitate Clinical Development', Frontiers in Immunology, vol. 8, 1361. https://doi.org/10.3389/fimmu.2017.013611664-3224PubMedCentral: PMC5660122http://hdl.handle.net/2164/9601Acknowledgments: The authors would like to acknowledge the funding support for this work from Scottish Enterprise [VNAR_001(2012)] and the Biotechnology and Biological Sciences Research Council (BB/K010905/1).3633485engJournal ArticleVNARsoloMERsingle chain binding domainSharkhumanizationhalf-life extensionpharmacokineticsQD ChemistryBiotechnology and Biological Sciences Research Council (BBSRC)BB/K010905/1QDJournal article10.3389/fimmu.2017.013618