Immune status is prognostic for poor survival in colorectal cancer patients and is associated with tumour hypoxia

Craig, Stephanie G.Humphries, Matthew PAlderdice, MatthewBingham, VictoriaRichman, Susan D.Loughrey, Maurice B.Coleman, Helen GViratham-Pulsawatdi, AmelieMcCombe, KrisMurray, Graeme I.Blake, AndrewDomingo, EnricRobineau, JamesBrown, LouiseFisher, DavidSeymour, Matthew T.Quirke, PhilBankhead, PeterMcQuaid, StephenLawler, MarkMcArt, Darragh G.Maughan, Tim S.James, Jacqueline ASalto-Tellez, Manuel2020-10-142020-10-142020-10-13Craig, S G, Humphries, M P, Alderdice, M, Bingham, V, Richman, S D, Loughrey, M B, Coleman, H G, Viratham-Pulsawatdi, A, McCombe, K, Murray, G I, Blake, A, Domingo, E, Robineau, J, Brown, L, Fisher, D, Seymour, M T, Quirke, P, Bankhead, P, McQuaid, S, Lawler, M, McArt, D G, Maughan, T S, James, J A & Salto-Tellez, M 2020, 'Immune status is prognostic for poor survival in colorectal cancer patients and is associated with tumour hypoxia', British Journal of Cancer, vol. 123, pp. 1280-1288. https://doi.org/10.1038/s41416-020-0985-50007-0920ORCID: /0000-0003-3981-2420/work/78069038https://hdl.handle.net/2164/15227Acknowledgements: PQ is a National Institute of Health Research Senior Investigator. Funding: The funders had no role in study design, collection, data analysis, or interpretation of the data. This study was supported by a Cancer Research UK Accelerator grant and carried out in collaboration with the stratified medicine consortium in colorectal cancer (S:CORT) which is jointly funded by the Medical Research Council and Cancer Research UK. Data availability The data are held within the Northern Ireland Biobank and the stratified medicine consortium in colorectal cancer (S:CORT), respectively, and are available on application.913787941931514engSDG 3 - Good Health and Well-beingCancer microenvironmentcolorectal cancertumour biomarkersMICROENVIRONMENTCARCINOMARC0254 Neoplasms. Tumors. Oncology (including Cancer)R MedicineOncologyCancer ResearchMedical Research Council (MRC)Cancer Research UKSupplementary DataRC0254RImmune status is prognostic for poor survival in colorectal cancer patients and is associated with tumour hypoxiaJournal article10.1038/s41416-020-0985-5http://www.scopus.com/inward/record.url?scp=85088133186&partnerID=8YFLogxK123