Kang, EunchaiSong, JuanLin, YutingPark, JaesukLee, Jennifer H.Hussani, QassimGu, YanGe, ShaoyuLi, WeidongHsu, Kuei-senBerninger, BenediktChristian, Kimberly M.Song, HongjunMing, Guo-li2020-07-272020-07-272019-08-06Kang, E, Song, J, Lin, Y, Park, J, Lee, J H, Hussani, Q, Gu, Y, Ge, S, Li, W, Hsu, K, Berninger, B, Christian, K M, Song, H & Ming, G 2019, 'Interplay between a Mental Disorder Risk Gene and Developmental Polarity Switch of GABA Action Leads to Excitation-Inhibition Imbalance', Cell Reports, vol. 28, no. 6, pp. 1419-1428.e3. https://doi.org/10.1016/j.celrep.2019.07.0242211-1247ORCID: /0000-0001-6884-622X/work/78070589https://hdl.handle.net/2164/14779Acknowledgments: We thank members of the Ming and Song laboratories for comments and suggestions, D. Johnson for technical support, and J. Schnoll for lab coordination. This work was supported by grants from the National Institutes of Health (NIH) (R01MH105128 and R35NS097370 to G.-L.M. and R37NS047344 to H.S.) and from the National Alliance for Research on Schizophrenia and Depression (NARSAD) to G.-L.M., H.S., and E.K. Author Contributions: E.K. and J.S contributed equally to this work. J.S. performed electrophysiological analysis and E.K. performed morphological analysis. Y.L. and K.-S.H. contributed to electrophysiology data collection, Y.G. and S.G. helped with some of the retrovirus production, and B.B. helped with rabies synaptic tracing. J.P., J.H.L., Q.H., W.L., and K.M.C. contributed to additional data collection. E.K., J.S., H.S., and G-L.M. designed the project and wrote the manuscript.142628032engSDG 3 - Good Health and Well-beingcircuit developmentdepolarizing GABADISC1excitation/inhibition imbalanceGABA polarity switchGABA signalinghomeostasismental disorderParvalbumin interneuronsynapse formationR Medicine (General)General Biochemistry,Genetics and Molecular BiologySupplementary DataR1Journal article10.1016/j.celrep.2019.07.024http://www.scopus.com/inward/record.url?scp=85069820573&partnerID=8YFLogxK286