Gray, RichardPatel, SmitaaIves, NatalieRick, CarolineWoolley, RebeccaMuzerengi, SharonGray, AlastairJenkinson, CrispinMcIntosh, EmmaWheatley, KeithWilliams, AdrianClarke, C. E.PD MED Collaborative Group2022-07-062022-07-062021-12-28Gray, R, Patel, S, Ives, N, Rick, C, Woolley, R, Muzerengi, S, Gray, A, Jenkinson, C, McIntosh, E, Wheatley, K, Williams, A, Clarke, C E & PD MED Collaborative Group 2021, 'Long-term Effectiveness of Adjuvant Treatment With Catechol-O-Methyltransferase or Monoamine Oxidase B Inhibitors Compared With Dopamine Agonists Among Patients With Parkinson Disease Uncontrolled by Levodopa Therapy : The PD MED Randomized Clinical Trial', JAMA Neurology, vol. 79, no. 2, pp. 131-140. https://doi.org/10.1001/jamaneurol.2021.47362168-6149Bibtex: 10.1001/jamaneurol.2021.4736ORCID: /0000-0001-6622-7839/work/164505666https://hdl.handle.net/2164/18799Funding/Support: The PD MED clinical trial was supported by funding from the Health Technology Assessment Programme of the UK National Institute for Health Research (project number 98/03/02), the UK Department of Health through March 2012 (University of Birmingham Clinical Trials Unit, supporting the salaries of Mss Ives and Patel), the UK Medical Research Council (Mr R. Gray), and Parkinson’s UK (Dr McIntosh). We thank all of the patients who agreed to enter the study, the many investigators who also contributed to the clinical trial, and NHS Digital, which provided data on mortality and data from the Hospital Episodes Statistics database. The investigators received no payment or other compensation for taking part in the PD MED clinical trial.19601009engR MedicineSupplementary DataSupplementary InformationRJournal article10.1001/jamaneurol.2021.4736792