Hague, William M.Callaway, LeonieChambers, JenniferChappell, LucyCoat, Suzettede Haan-Jebbink, JiskaDekker, MarloesDixon, PeterDodd, JodieFuller, MariaGordijn, SanneGraham, DorothyHeikinheimo, OskariHennessy, AnnemarieKaaja, RistoKhong, Teck YeeLampio, LauraLouise, JennieMakris, AngelaMarkus, CoreyMarschall, Hanns-UlrichMiddleton, PhilippaMol, Ben W.Morris, JonathanNewnham, John P.Ovadia, CarolinePeek, MichaelShand, AntoniaStark, MichaelThornton, JimTimonen, SusannaWalker, SusanWarrilow, DavidWilliamson, Catherine2021-05-142021-05-142021Hague, W M, Callaway, L, Chambers, J, Chappell, L, Coat, S, de Haan-Jebbink, J, Dekker, M, Dixon, P, Dodd, J, Fuller, M, Gordijn, S, Graham, D, Heikinheimo, O, Hennessy, A, Kaaja, R, Khong, T Y, Lampio, L, Louise, J, Makris, A, Markus, C, Marschall, H-U, Middleton, P, Mol, B W, Morris, J, Newnham, J P, Ovadia, C, Peek, M, Shand, A, Stark, M, Thornton, J, Timonen, S, Walker, S, Warrilow, D & Williamson, C 2021, 'A multi-centre, open label, randomised, parallel-group, superiority Trial to compare the efficacy of URsodeoxycholic acid with RIFampicin in the management of women with severe early onset Intrahepatic Cholestasis of pregnancy : the TURRIFIC randomised trial', BMC Pregnancy and Childbirth, vol. 21, no. 1, 51. https://doi.org/10.1186/s12884-020-03481-y1471-2393RIS: urn:8427CB7496C12F2E3F911F9C1A11CEA6RIS: Hague2021PubMedCentral: PMC7802989https://hdl.handle.net/2164/16464Funding The study sponsor and the funder (National Health and Medical Research Council (NHMRC) Medical Research Future Fund (MRFF) Lifting Clinical Trials and Registries Capacity (LCTRC) Grant Opportunity) have had no role in the study design; the collection, management, analysis, and interpretation of the data; the final writing of the report; and the decision to submit the report for publication.14854572engSDG 3 - Good Health and Well-beingIntrahepatic cholestasis of pregnancyCholestatic pruritusBile acidsUrsodeoxycholic acidRifampicinMaternal and neonatal health outcomesR MedicineRG Gynecology and obstetricsSupplementary InformationRRGJournal article10.1186/s12884-020-03481-y211