Meadows, Allison MHan, KimSingh, KomudiMurgia, AntonioMcNally, Ben DWest, James AHuffstutler, Rebecca DPowell-Wiley, Tiffany MBaumer, YvonneGriffin, Julian LSack, Michael N2023-10-252023-10-252023-05-19Meadows, A M, Han, K, Singh, K, Murgia, A, McNally, B D, West, J A, Huffstutler, R D, Powell-Wiley, T M, Baumer, Y, Griffin, J L & Sack, M N 2023, 'N-arachidonylglycine is a caloric state-dependent circulating metabolite which regulates human CD4+T cell responsiveness', iScience, vol. 26, no. 5, 106578. https://doi.org/10.1016/j.isci.2023.1065782589-0042PubMedCentral: PMC10148119ORCID: /0000-0003-1336-7744/work/145602734https://hdl.handle.net/2164/22019Acknowledgments We thank Drs. Zoe Hall and Sonia Liggi of the University of Cambridge Biochemistry Department for their contributions to metabolomics analysis and data processing. Shahin Hassanzadeh of the Laboratory of Mitochondrial Biology and Metabolism for developing the PBMC RNAseq library.Matthew Rodman of the Laboratory of Mitochondrial Biology and Metabolism for preparing lean/obese samples. Dr. Duck-Yeon Lee of the NHLBI Biochemistry Core for NAGly analysis in cell culture. Special thanks to the National Institutes of Health Oxford-Cambridge Scholars Program and the International Biomedical Research Alliance for their sponsorship and support. Funding: NHLBI Division of Intramural Research (MNS – ZIA-HL005199) and the UK MRC (JLG – MR/P011705/2; UKDRI-5002; MAPUK).194404587engSDG 3 - Good Health and Well-beingHuman metabolismImmunologyLipidomicsMetabolomicsTranscriptomicsR MedicineMedical Research Council (MRC)MR/P011705/2Supplementary InformationRJournal article10.1016/j.isci.2023.106578265