Steinmüller, S.A.M.Thompson, K.Alenfelder, J.Drube, J.Hoffmann, CarstenKostenis, E.Thompson, D.Hislop, J.N.2025-07-242025-07-242025-11Steinmüller, S A M, Thompson, K, Alenfelder, J, Drube, J, Hoffmann, C, Kostenis, E, Thompson, D & Hislop, J N 2025, 'Identification of a regulatory sequence within the third intracellular loop that governs β-arrestin binding to the muscarinic M5 receptor', Cellular Signalling, vol. 135, 112004. https://doi.org/10.1016/j.cellsig.2025.1120040898-6568RIS: urn:08A4C03EBE099045BA790D3EDF617D47ORCID: /0000-0003-0948-9458/work/188340162https://hdl.handle.net/2164/25753Open Access via the Elsevier agreement We would like to thank M. Bouvier (University of Montreal, Canada) for providing the GEMTA constructs for BRET experiments, K. Pfleger (University of Western Australia) for providing luciferase tagged β-arrestin1 and 2, and GRK2 constructs, A. Inoue for generously supplying the ∆β-arrestin1/2 CRISPR/Cas9 edited cells, and A. Tobin for providing the M1 DREADD construct. We also thank B. Platt (University of Aberdeen) for technical guidance for calcium imaging.148582362engR Medicine (General)Supplementary DataDASR1Identification of a regulatory sequence within the third intracellular loop that governs β-arrestin binding to the muscarinic M5 receptorJournal article10.1016/j.cellsig.2025.112004https://www.sciencedirect.com/science/article/pii/S089865682500419X135