Tau Filament Self-Assembly and Structure : Tau as a Therapeutic Target.

Oakley, SebastianMaina, Mahmoud B.Marshall, Karen E.Al-Hilaly, Youssra KHarrington, Charles RWischik, Claude MSerpell, Louise C2020-11-122020-11-122020-11-12Oakley, S, Maina, M B, Marshall, K E, Al-Hilaly, Y K, Harrington, C R, Wischik, C M & Serpell, L C 2020, 'Tau Filament Self-Assembly and Structure : Tau as a Therapeutic Target.', Frontiers in Neurology, vol. 11, 590754. https://doi.org/10.3389/fneur.2020.5907541664-2295ORCID: /0000-0003-2250-3920/work/173415876https://hdl.handle.net/2164/15357Acknowledgments: The authors are grateful to the Alzheimer's Society and Alzheimer's Research UK for support. Funding: MBM was funded by Alzheimer's Society (AS-PG-16b-010). SO, KEM, and YA-H are funded by WisTa Laboratories Ltd., (PAR1596). LCS was supported by ARUK South Coast Network.231699611engtauTaupathiesAlzheimer's diseaseTau aggregation inhibitorsin vitro modelsself-assemblyfilamentstau aggregation inhibitorstauopathiesPROTEIN-TAUMETHYLENE-BLUENEUROFIBRILLARY TANGLESALZHEIMERS-DISEASE BRAINAlzheimer&aposALPHA-SYNUCLEINs diseaseIN-VITROAMYLOID-BETAAGGREGATION INHIBITOR THERAPYMOUSE MODELPAIRED HELICAL FILAMENTSR MedicineClinical NeurologyNeurologyArthritis Research UK (ARUK)RTau Filament Self-Assembly and Structure : Tau as a Therapeutic Target.Journal article10.3389/fneur.2020.590754http://www.scopus.com/inward/record.url?scp=85096643300&partnerID=8YFLogxK11