Hendawy, O. M.Gomaa, Hesham A.M.Alzarea, Sami I.Alshammari, Mutariah S.Mohamed, Fatma A.M.Mostafa, Yaser A.Abdelazeem, Ahmed H.Abdelrahman, Mostafa H.Trembleau, LaurentYoussif, Bahaa G.M.2022-08-232022-08-232021-11-01Hendawy, O M, Gomaa, H A M, Alzarea, S I, Alshammari, M S, Mohamed, F A M, Mostafa, Y A, Abdelazeem, A H, Abdelrahman, M H, Trembleau, L & Youssif, B G M 2021, 'Novel 1,5-diaryl pyrazole-3-carboxamides as selective COX-2/sEH inhibitors with analgesic, anti-inflammatory, and lower cardiotoxicity effects', Bioorganic Chemistry, vol. 116, 105302. https://doi.org/10.1016/j.bioorg.2021.1053020045-2068ORCID: /0000-0001-6376-9077/work/100717603https://hdl.handle.net/2164/19093Funding Information: The authors extend their appreciation to the Deanship of Scientific Research at Jouf University for funding this work through research grant number (DSR2020-04-421 )141697097engCardiomyopathyCOX-2/sEHNSAIDSPyrazolesQD ChemistryBiochemistryMolecular BiologyDrug DiscoveryOrganic ChemistrySupplementary Datahttps://doi. org/10.1016/j.bioorg.2021.105302QDJournal article10.1016/j.bioorg.2021.105302http://www.scopus.com/inward/record.url?scp=85113795824&partnerID=8YFLogxK116