Wang, Shui PingRubio, Luis A.Duncan, Sylvia H.Donachie, Gillian E.Holtrop, GrietjeLo, GalianaFarquharson, Freda M.Wagner, JosefParkhill, JulianLouis, PetraWalker, AlanFlint, Harry J.2020-10-192020-10-192020-09-08Wang, S P, Rubio, L A, Duncan, S H, Donachie, G E, Holtrop, G, Lo, G, Farquharson, F M, Wagner, J, Parkhill, J, Louis, P, Walker, A & Flint, H J 2020, 'Pivotal roles for pH, lactate and lactate-utilizing bacteria in the stability of a human colonic microbial ecosystem', mSystems, vol. 5, no. 5, e00645-20. https://doi.org/10.1128/mSystems.00645-202379-5077ORCID: /0000-0003-2115-2399/work/80462165ORCID: /0000-0002-4903-0978/work/80462927ORCID: /0000-0001-5099-8495/work/80463414https://hdl.handle.net/2164/15248ACKNOWLEDGEMENTS: The authors would like to thank Donna Henderson for carrying out GC analysis, and Dr Helen Kettle for help with microPop. Thanks also to the Wellcome Sanger Institute’s core sequencing team and CGEBM at the University of Aberdeen for carrying out the Illumina MiSeq sequencing of 16S rRNA genes. The authors would also like to acknowledge the support of the Maxwell compute cluster funded by the University of Aberdeen.183622636engSDG 3 - Good Health and Well-beingLactateLactate-utilizing bacteriapHShort chain fatty acidsMathematical modellingShort-chain fatty acidsPHMathematical modelingMETABOLITESPOPULATIONSCOMMUNITIESlactate-utilizing bacteriaPROPIONATESHORT-BOWEL SYNDROMECHAIN FATTY-ACIDSmathematical modelingFERMENTATIONEUBACTERIUM-HALLIIBUTYRATElactateshort-chain fatty acidsTOOLR MedicineGeneticsEcology, Evolution, Behavior and SystematicsMolecular BiologyPhysiologyBiochemistryComputer Science ApplicationsMicrobiologyModelling and SimulationSupplementary DataRPivotal roles for pH, lactate and lactate-utilizing bacteria in the stability of a human colonic microbial ecosystemJournal article10.1128/mSystems.00645-20http://www.scopus.com/inward/record.url?scp=85092055623&partnerID=8YFLogxK55