Impact of secreted glucanases upon the cell surface and fitness of Candida albicans during colonisation and infection.

Ma, QinxiPradhan, ArnabLeaves, IanHickey, EmerRoselletti, ElenaDambuza, IvyLarcombe, Daniel Ede Assis, Leandro JoseWilson, DuncanErwig, Lars PNetea, Mihai GChilders, Delma SBrown, Gordon DGow, Neil A RBrown, Alistair J P2024-08-132024-08-132024-06Ma, Q, Pradhan, A, Leaves, I, Hickey, E, Roselletti, E, Dambuza, I, Larcombe, D E, de Assis, L J, Wilson, D, Erwig, L P, Netea, M G, Childers, D S, Brown, G D, Gow, N A R & Brown, A J P 2024, 'Impact of secreted glucanases upon the cell surface and fitness of Candida albicans during colonisation and infection.', The Cell Surface, vol. 11, 100128. https://doi.org/10.1016/j.tcsw.2024.1001282468-2330PubMedCentral: PMC11208952ORCID: /0000-0003-2869-7332/work/165793018https://hdl.handle.net/2164/24024Acknowledgements We thank Raif Yuecel and Attila Bebes in the Exeter Centre for Cytomics for their help with the cytometry, and Annie Phillips-Brookes, Jamie Harvey and the BSU staff for their support with the animal experimentation. We are grateful to Karen Moore, Paul O’Neill and Jemima Onime in the University of Exeter Sequencing Facility University of Exeter Sequencing Facility for their help with the barcode sequencing. We also thank Paulina Cherek in the Bioimaging Facility in Exeter Biosciences for her help with the transmission electron microscopy, and Darren Thomson in the MRC Centre for Medical Mycology for his support for our the DeltaVision imaging. For the purpose of open access, the author has applied a CC BY public copyright licence to any Author Accepted Manuscript version arising from this submission.136249950engCandida albicansCell wallEng1 endoglucanaseGut colonisationVirulenceXog1 exoglucanaseβ-glucan shavingR Medicine (General)Applied Microbiology and BiotechnologyMolecular BiologyCell BiologyMicrobiologySupplementary Datahttps://ars.els-cdn.com/content/image/1-s2.0-S2468233024000100-mmc1.pdfhttps://ars.els-cdn.com/content/image/1-s2.0-S2468233024000100-mmc2.pdfhttps://ars.els-cdn.com/content/image/1-s2.0-S2468233024000100-mmc3.pdfhttps://ars.els-cdn.com/content/image/1-s2.0-S2468233024000100-mmc4.pdfhttps://ars.els-cdn.com/content/image/1-s2.0-S2468233024000100-mmc5.pdfhttps://ars.els-cdn.com/content/image/1-s2.0-S2468233024000100-mmc6.pdfhttps://ars.els-cdn.com/content/image/1-s2.0-S2468233024000100-mmc7.pdfR1Impact of secreted glucanases upon the cell surface and fitness of Candida albicans during colonisation and infection.Journal article10.1016/j.tcsw.2024.100128https://www.sciencedirect.com/science/article/pii/S2468233024000100?via%3Dihub11