Topological dynamics of an intrinsically disordered N-terminal domain of the human androgen receptor

Sheikhhassani, VahidScalvini, BarbaraNg, JulianHeling, Laurens W H JAyache, YosriEvers, Tom M JEstébanez-Perpiñá, EvaMcEwan, Iain JMashaghi, Alireza2022-11-302022-11-302022-06Sheikhhassani, V, Scalvini, B, Ng, J, Heling, L W H J, Ayache, Y, Evers, T M J, Estébanez-Perpiñá, E, McEwan, I J & Mashaghi, A 2022, 'Topological dynamics of an intrinsically disordered N-terminal domain of the human androgen receptor', Protein science : a publication of the Protein Society, vol. 31, no. 6, e4334. https://doi.org/10.1002/pro.43340961-8368PubMedCentral: PMC9134807https://hdl.handle.net/2164/19653ACKNOWLEDGEMENTS We are thankful to Eugene Shakhnovich (Harvard University) for critical reading of the manuscript, and to Peter Bolhuis and Ioana Ilie (University of Amsterdam) for technical discussions. The research in Mashaghi lab is supported by funding from Muscular Dystrophy Association (USA), Grant Number MDA628071, and Dutch Research Council (Nederlandse Organisatie voor Wetenschappelijk Onderzoek) through NWA-IDG (NWA.1228.192.309) and Open Competition XS (OCENW.XS.076).173645995engSDG 3 - Good Health and Well-beingAndrogen Receptor Antagonists/chemistryDNAHumansMaleProstatic Neoplasms/metabolismProtein DomainsReceptors, Androgen/chemistryR Medicine (General)R1Topological dynamics of an intrinsically disordered N-terminal domain of the human androgen receptorJournal article10.1002/pro.4334316