Ahmed, SuaadBusetti, AlessandroFotiadou, ParthenaVincy Jose, NishaReid, SarahGeorgieva, MarietaBrown, SamanthaDunbar, HayleyBeurket-Ascencio, GloriaDelday, Margaret IEttorre, AnnaMulder, Imke E2019-11-012019-11-012019-09-20Ahmed, S, Busetti, A, Fotiadou, P, Vincy Jose, N, Reid, S, Georgieva, M, Brown, S, Dunbar, H, Beurket-Ascencio, G, Delday, M I, Ettorre, A & Mulder, I E 2019, 'In vitro Characterization of Gut Microbiota-Derived Bacterial Strains With Neuroprotective Properties', Frontiers in cellular neuroscience, vol. 13, 402. https://doi.org/10.3389/fncel.2019.004021662-5102PubMedCentral: PMC6763572https://hdl.handle.net/2164/13208Acknowledgments The authors are grateful to Dr. Nicole Reichardt and the 4D Pharma Isolation Team for their technical assistance with bacterial culture. Funding This work was privately funded by 4D Pharma PLC. The authors of the study, who are employees of (or in the case of MID, are funded by) 4D Pharma Research Ltd., a wholly owned subsidiary of the funder, were responsible for the design and execution of the study, as well as the analysis of the results obtained. Author Contributions In vitro experiments: AE, SA, and AB designed the experiments; SA, PF, NV, MG, SB, GB-A, and MD performed the majority of the in vitro experiments; SR, HD, and AB validated, performed, and analyzed the microbiological-related data output; AE coordinated and managed the research project; AE, SA, PF, and AB analyzed the data. IM oversaw the overall research plan. AE wrote the manuscript with the assistance of SA and AB. All authors have read and commented on the manuscript and have approved the final version of the manuscript. Data Availability: 16S gene sequences for MRx0005 and MRx0029 are disclosed in International Patent Publication Nos. WO2018/229189 and WO2018/229216, respectively, filed by 4D Pharma Research Ltd. The data supporting the findings in this paper are available within the article and its Supplementary Information Files.2554983enggut microbiota-derived bacterial strainsmicrobiomeneurodegenerative diseasesneuroinflammationneuroprotectionoxidative stressgut-brain axisshort-chain fatty acidscellsbrain axisinvolvementdisordersmodelgas-chromatographydistasonischain fatty-acidsstressParkinson's diseaseQH301 BiologySupplementary DataQH301Journal article10.3389/fncel.2019.00402https://www.frontiersin.org/articles/10.3389/fncel.2019.00402/full#S1013