McCartney, Daniel L.Zhang, FutaoHillary, Robert F.Zhang, QianStevenson, Anna J.Walker, Rosie M.Bermingham, Mairead L.Morris, Stewart W.Campbell, ArchieMurray, Alison D.Whalley, Heather C.Porteous, David J.Evans, Kathryn L.Chandra, TamirDeary, Ian J.McIntosh, Andrew M.Yang, JianVisscher, Peter M.McRae, Allan F.Marioni, Riccardo E.2020-01-092020-01-092019-12-31McCartney, D L, Zhang, F, Hillary, R F, Zhang, Q, Stevenson, A J, Walker, R M, Bermingham, M L, Morris, S W, Campbell, A, Murray, A D, Whalley, H C, Porteous, D J, Evans, K L, Chandra, T, Deary, I J, McIntosh, A M, Yang, J, Visscher, P M, McRae, A F & Marioni, R E 2019, 'An epigenome-wide association study of sex-specific chronological ageing', Genome Medicine, vol. 12, 1. https://doi.org/10.1186/s13073-019-0693-z, https://doi.org/10.7488/ds/27091756-994XORCID: /0000-0003-4915-4847/work/76976622https://hdl.handle.net/2164/13485Availability of Data and Material According to the terms of consent for GS participants, access to individual-level data (omics and phenotypes) must be reviewed by the GS Access Committee. Applications should be made to access@generationscotland.org. Full summary statistics for the analyses presented are publicly available online at https://doi.org/10.7488/ds/2709. Funding GS received core support from the Chief Scientist Office of the Scottish Government Health Directorates (CZD/16/6) and the Scottish Funding Council (HR03006). Genotyping and DNA methylation profiling of the GS samples was carried out by the Genetics Core Laboratory at the Clinical Research Facility, University of Edinburgh, Edinburgh, Scotland and was funded by the Medical Research Council UK and the Wellcome Trust (Wellcome Trust Strategic Award “STratifying Resilience and Depression Longitudinally” ([STRADL; Reference 104036/Z/14/Z]). DLM and REM are supported by Alzheimer’s Research UK major project grant ARUK-PG2017B-10. PMV and AFM are supported by the NHMRC Fellowship Scheme (1078037, 1078901, and 1083656). JY is supported by an ARC Future Fellowship (FT180100186). RFH and AJS are supported by funding from the Wellcome Trust 4-year PhD in Translational Neuroscience – training the next generation of basic neuroscientists to embrace clinical research [108890/Z/15/Z]. CH and TB are supported by an MRC University Unit Programme Grant MC_UU_00007/10 (QTL in Health and Disease). Acknowledgements We are grateful to all the families who took part, the general practitioners and the Scottish School of Primary Care for their help in recruiting them, and the whole GS team that includes interviewers, computer and laboratory technicians, clerical workers, research scientists, volunteers, managers, receptionists, healthcare assistants, and nurses.112577331engSDG 3 - Good Health and Well-beingDNA methylationageingsexual dimorphismX-chromosomeGeneration ScotlandR Medicine (General)Chief Scientist Office (CSO)CZD/16/6Scottish Funding CouncilHR03006Medical Research Council (MRC)MC_UU_00007/10Wellcome Trust104036/Z/14/ZAlzheimers Research UKARUK-PG2017B-10Supplementary DataR1Journal article10.1186/s13073-019-0693-z12