Siemienowicz, Katarzyna JFurmanska, KlaudiaFilis, PanagiotisTalia, ChiaraThomas, JenniferFowler , Paul ARae, Mick TColin Duncan, W.2022-02-062022-02-062021-04-05Siemienowicz, K J, Furmanska, K, Filis, P, Talia, C, Thomas, J, Fowler , P A, Rae, M T & Colin Duncan, W 2021, 'Pubertal FGF21 deficit is central in the metabolic pathophysiology of an ovine model of polycystic ovary syndrome', Molecular and Cellular Endocrinology, vol. 525, 111196. https://doi.org/10.1016/j.mce.2021.1111960303-7207ORCID: /0000-0002-4831-9075/work/90173080https://hdl.handle.net/2164/18033Acknowledgements The authors wish to acknowledge Joan Docherty, John Hogg, Marjorie Thomson, Peter Tennant and James Nixon and the staff at the Marshall Building, University of Edinburgh for their excellent animal husbandry. Dr Kirsten Hogg, Dr Fiona Connolly, Dr Junko Nio443 Kobayashi, Dr Avi Lerner and Lyndsey Boswell helped with tissue collection. Funding This work was funded by Medical Research Council (MRC) project grants (G0500717; G0801807; G0802782; MR/P011535/1) and supported by the MRC Centre for Reproductive Health (MR/N022556/1).12757880engSubstantive connection via eligible employment contractSDG 3 - Good Health and Well-beingpolycystic ovaries syndromeFibroblast Growth Factor 21 (FGF21)metabolismprenatal programmingadrogensPolycystic ovary syndromeAndrogensFibroblast growth factor 21 (FGF21)Prenatal programmingMetabolismR MedicineEndocrinologyMolecular BiologyBiochemistryMedical Research Council (MRC)G0500717G0801807G0802782MR/P011535/1MR/N022556/1RJournal article10.1016/j.mce.2021.111196http://www.scopus.com/inward/record.url?scp=85100622422&partnerID=8YFLogxK525