Neuroprotection of Cholinergic Neurons with a Tau Aggregation Inhibitor and Rivastigmine in an Alzheimer's-like Tauopathy Mouse Model

Zadrozny, MaciejDrapich, PatrycjaGasiorowska-Bien, AnnaNiewiadomski, WiktorHarrington, Charles RWischik, Claude MRiedel, GernotNiewiadomska, Grazyna2024-05-232024-05-232024-04-06Zadrozny, M, Drapich, P, Gasiorowska-Bien, A, Niewiadomski, W, Harrington, C R, Wischik, C M, Riedel, G & Niewiadomska, G 2024, 'Neuroprotection of Cholinergic Neurons with a Tau Aggregation Inhibitor and Rivastigmine in an Alzheimer's-like Tauopathy Mouse Model', Cells, vol. 13, no. 7, 642. https://doi.org/10.3390/cells130706422073-4409PubMedCentral: PMC11011792ORCID: /0000-0003-2250-3920/work/173415865https://hdl.handle.net/2164/23504Acknowledgments The authors acknowledge Joanna Lewandowska for the technical support with the perfusion of mice, brain collections and embedding and assisting in the procedures of histological staining; and Adrianna Wysocka for providing her proprietary Makro tool, enabling the objectification and standardization of the ROI measurements by using Fiji. S1D12 was provided by Dr Soumya Palliyil, Scottish Biologics Facility, University of Aberdeen, Aberdeen, UK.275187145engHumansMiceAnimalsInfantRivastigmine/pharmacologyAlzheimer Disease/metabolismtau Proteins/metabolismCholinesterase Inhibitors/pharmacologyAcetylcholinesterase/metabolismNeuroprotectionCholinergic Neurons/metabolismTauopathies/drug therapyCholinergic AgentsMice, TransgenicR MedicineRNeuroprotection of Cholinergic Neurons with a Tau Aggregation Inhibitor and Rivastigmine in an Alzheimer's-like Tauopathy Mouse ModelJournal article10.3390/cells13070642137