Ponnusamy, SuriyanCoss, Christopher C.Thiyagarajan, ThirumagalWatts, KateHwang, Dong-JinHe, YaliSelth, Luke A.McEwan, Iain J.Duke, Charles B.Pagadala, JayaprakashSingh, GeetikaWake, Robert W.Ledbetter, ChristopherTilley, Wayne D.Moldoveanu, TudorDalton, James T.Miller, Duane D.Narayanan, Ramesh2018-10-032018-10-032017-11Ponnusamy, S, Coss, C C, Thiyagarajan, T, Watts, K, Hwang, D-J, He, Y, Selth, L A, McEwan, I J, Duke, C B, Pagadala, J, Singh, G, Wake, R W, Ledbetter, C, Tilley, W D, Moldoveanu, T, Dalton, J T, Miller, D D & Narayanan, R 2017, 'Novel Selective Agents for the Degradation of Androgen Receptor Variants to Treat Castration-Resistant Prostate Cancer', Cancer Research, vol. 77, no. 22, pp. 6282-6298. https://doi.org/10.1158/0008-5472.CAN-17-09760008-5472http://hdl.handle.net/2164/11216Acknowledgements: The authors thank Mr. Maron Lee Barrett and Ms. Mayra Star for their technical help. The authors thank Dr. Dejian Ma for his technical help with the NMR studies. The authors thank the UTHSC and St. Jude NMR core for their help with the NMR studies. The authors thank Drs. Robert Getzenberg and Michael Mohler for providing useful comments on the manuscript. The authors thank Ms. Brandy Grimes for her help with tissue procurement. The authors thank Dr. Daniel Johnson of UT BioCore for microarray data analysis and Mr. Lorne Rose of UT-MRC core for microarray studies. Funding Source: The research presented in this manuscript was supported by a research funding provided by GTx, Inc. Memphis, TN to R. Narayanan and by a research funding provided by West Cancer Center to R. Narayanan.177135320engSDG 3 - Good Health and Well-beingAndrogen Receptor (AR)Selective Androgen Receptor Degraders (SARDs)AR Splice Variants (AR-SV)prostate cancerCastration-Resistant Prostate Cancer (CRPC)AR antagonistAF-1-binding AR antagonistAR translocation inhibitorAR pan-antagonistR Medicine (General)Supplementary DataR1Journal article10.1158/0008-5472.CAN-17-09767722