Sadatsafavi, MohsenTran, Trung NScelo, GhislaineTsai, Ming-JuBusby, JohnEmmanuel, BenjaminHeaney, Liam GJenkins, ChristineHoyte, Flavia L.Canonica, Giorgio WalterKatial, RohitHeffler, EnricoWang, EileenPuggioni, FrancescaWechsler, Michael EArdusso, Ledit R. F.Maspero, Jorge FSivori, MartinEmmas, CathyMenzies-Gow, AndrewStjepanovic, NedaBosnic-Anticevich, Sinthia ZCochrane,, BelindaDenton, EveGibson, Peter G.Hew, MarkMiddleton, Peter GPeters, Matthew JBrusselle, GuyLouis, RenaudSchleich, FlorenceChristoff, George CPopov, Todor ABergeron , CelineBhutani, MohitChapman, Kenneth RCôté, AndréanneCouillard, SimonDorscheid, Delbert R.Jiménez-Maldonado, LibardoSolarte, IvanTorres-Duque, Carlos A.Hansen, SusannePorsbjerg, Celeste M.Suppli Ulrik, CharlotteAltraja, AlanBourdin, ArnaudExarchos, Konstantinos P.Gogali, AthenaKostikas, KonstantinosMakris, Michael P.Papaioannou, Andriana I.Mitchell, PatrickIwanaga, TakashiNagano, TatsuyaTohda, YujiAl-Ahmad, Mona SLarenas-Linnemann, DésiréeBøgvald Aarli, BerntKuna, PiotrLoureiro, Claudia ChavesAl-Lehebi, RiyadBulkhi, Adeeb A.Chen, WenjiaJuang, Yah RuKoh, Mariko SiyueLiu, AnqiRhee, Chin KookCosio, Borja G.Perez de Llano, LuisPerng, Diahn WarngSheu, Chau-ChyunWang, Hao-ChienMahboub, BassamSalameh, LailaJackson, David JPatel, Pujan HPfeffer, Paul ELugogo, NjiraPleasants, Roy AltonBeastall, AaronBulathsinhala, LakminiCarter, VictoriaEleangovan, NevaashniFletton, KirstyTownend, JohnMurray, Ruth BPrice, DavidISAR SOLAR II Working Group2025-05-202025-05-202025-05-19Sadatsafavi, M, Tran, T N, Scelo, G, Tsai, M-J, Busby, J, Emmanuel, B, Heaney, L G, Jenkins, C, Hoyte, F L, Canonica, G W, Katial, R, Heffler, E, Wang, E, Puggioni, F, Wechsler, M E, Ardusso, L R F, Maspero, J F, Sivori, M, Emmas, C, Menzies-Gow, A, Stjepanovic, N, Bosnic-Anticevich, S Z, Cochrane, B, Denton, E, Gibson, P G, Hew, M, Middleton, P G, Peters, M J, Brusselle, G, Louis, R, Schleich, F, Christoff, G C, Popov, T A, Bergeron , C, Bhutani, M, Chapman, K R, Côté, A, Couillard, S, Dorscheid, D R, Jiménez-Maldonado, L, Solarte, I, Torres-Duque, C A, Hansen, S, Porsbjerg, C M, Suppli Ulrik, C, Altraja, A, Bourdin, A, Exarchos, K P, Gogali, A, Kostikas, K, Makris, M P, Papaioannou, A I, Mitchell, P, Iwanaga, T, Nagano, T, Tohda, Y, Al-Ahmad, M S, Larenas-Linnemann, D, Bøgvald Aarli, B, Kuna, P, Loureiro, C C, Al-Lehebi, R, Bulkhi, A A, Chen, W, Juang, Y R, Koh, M S, Liu, A, Rhee, C K, Cosio, B G, Perez de Llano, L, Perng, D W, Sheu, C-C, Wang, H-C, Mahboub, B, Salameh, L, Jackson, D J, Patel, P H, Pfeffer, P E, Lugogo, N, Pleasants, R A, Beastall, A, Bulathsinhala, L, Carter, V, Eleangovan, N, Fletton, K, Townend, J, Murray, R B, Price, D & ISAR SOLAR II Working Group 2025, 'Prevention of cardiovascular and other systemic adverse outcomes in patients with asthma treated with biologics', American Journal of Respiratory and Critical Care Medicine. https://doi.org/10.1164/rccm.202501-0246OC1073-449Xhttps://hdl.handle.net/2164/25479We would like to acknowledge Ms Pui Yee Lai (MA) of the Observational and Pragmatic Research Institute (OPRI), Singapore, for editorial and formatting assistance which supported the development of this publication. We would also like to extend a big thank you to all ISAR Collaborators (see Online Supplement).414406engSDG 3 - Good Health and Well-beingDiabetes Mellitusadverse cardiac eventcohort studiesR Medicine (General)Supplementary DataDASR1Journal article10.1164/rccm.202501-0246OC