Large-scale RNA-Seq mining reveals ciclopirox olamine induces TDP-43 cryptic exons

Sinha, Irika R.Sandal, Parker S.Spence, HollyBurns, Grace D.Mallika, Aswathy PeethambaranAbbasinejad, FatemehIrwin, Katherine E.Cruz, Anna Lourdes F.Wang, VaniaMarx, Shaelyn R.Rodríguez, Josué LlamasLangmead, BenGregory, Jenna M.Wong, Philip C.Ling, Jonathan P.2025-10-272025-07-25Sinha, I R, Sandal, P S, Spence, H, Burns, G D, Mallika, A P, Abbasinejad, F, Irwin, K E, Cruz, A L F, Wang, V, Marx, S R, Rodríguez, J L, Langmead, B, Gregory, J M, Wong, P C & Ling, J P 2025, 'Large-scale RNA-Seq mining reveals ciclopirox olamine induces TDP-43 cryptic exons', Nature Communications, vol. 16, 6878. https://doi.org/10.1038/s41467-025-62004-52041-1723ORCID: /0000-0002-1628-6790/work/195320914ORCID: /0000-0003-3337-4079/work/195321089https://hdl.handle.net/2164/26309152051692engSDG 3 - Good Health and Well-beingAmyotrophic lateral sclerosisData miningNeurodegenerationRNA SplicingQD ChemistryGeneral ChemistryGeneral Biochemistry,Genetics and Molecular BiologyGeneralGeneral Physics and AstronomySupplementary DataDASLinkQDLarge-scale RNA-Seq mining reveals ciclopirox olamine induces TDP-43 cryptic exonsJournal article10.1038/s41467-025-62004-5http://www.scopus.com/inward/record.url?scp=105011734706&partnerID=8YFLogxK