Jefferson, EmilyCole, ChristianMumtaz, ShahzadUrwin, EsmondLea, DanielMacdonald, CalumBest, JosephMasood, ErumMilligan, GordonJohnston, JennyHorban, ScottBirced, IpekHall, ChristopherJackson, Aaron SCollins, ClareRising, SamDodsley, CharlotteHampton, JillHadfield, AndrewTarr, SimonPanagi, VasilikiLavagna, JosephJackson, TracyChuter, AntonyBeggs, JillianWard, Helenvon Ziegenweidt, JulieBurns, FrancesMartin, JoanneSebire, NeilMorris, CaroleBradley, DeclanBaxter, RobAhonen-Bishopp, AnniSmith, PaulShoemark, AmeliaValdes, Ana MOllivere, BenjaminManisty, CharlotteEyre, DavidGallant, StephanieJoy, GeorgeMcAuley, AndrewConnell, DavidNorthstone, KateJeffery, KatieDi Angelantonio, EmanueleMcMahon, AmyWalker, MatSemple, Malcolm GracieLawrence, EmmaDavies, BethanBaillie, John KennethTang, MingLeeming, GaryPower, LindaBreeze, ThomasOrton, ChrisPierce, IainHall, IanLadhani, ShamezGillson, NatalieWhitaker, MatthewShallcross, LauraSeymour, DavidVarma, SusheelReilly, GerryMorris, AndrewHopkins, SusanSheikh, AzizQuinlan, PhilipCox, SamuelGiles, Thomas CharlesAdejumo, SamSantos, RobertoMartinez-Queipo, MagdalenaSims, Jessica MaiMurray, Duncan2023-10-252023-10-252022-12-27Jefferson, E, Cole, C, Mumtaz, S, Urwin, E, Lea, D, Macdonald, C, Best, J, Masood, E, Milligan, G, Johnston, J, Horban, S, Birced, I, Hall, C, Jackson, A S, Collins, C, Rising, S, Dodsley, C, Hampton, J, Hadfield, A, Tarr, S, Panagi, V, Lavagna, J, Jackson, T, Chuter, A, Beggs, J, Ward, H, von Ziegenweidt, J, Burns, F, Martin, J, Sebire, N, Morris, C, Bradley, D, Baxter, R, Ahonen-Bishopp, A, Smith, P, Shoemark, A, Valdes, A M, Ollivere, B, Manisty, C, Eyre, D, Gallant, S, Joy, G, McAuley, A, Connell, D, Northstone, K, Jeffery, K, Di Angelantonio, E, McMahon, A, Walker, M, Semple, M G, Lawrence, E, Davies, B, Baillie, J K, Tang, M, Leeming, G, Power, L, Breeze, T, Orton, C, Pierce, I, Hall, I, Ladhani, S, Gillson, N, Whitaker, M, Shallcross, L, Seymour, D, Varma, S, Reilly, G, Morris, A, Hopkins, S, Sheikh, A, Quinlan, P, Cox, S, Giles, T C, Adejumo, S, Santos, R, Martinez-Queipo, M, Sims, J M & Murray, D 2022, 'A Hybrid Architecture (CO-CONNECT) to Facilitate Rapid Discovery and Access to Data Across the United Kingdom in Response to the COVID-19 Pandemic : Development Study', Journal of Medical Internet Research, vol. 24, no. 12, e40035 , pp. e40035. https://doi.org/10.2196/preprints.40035, https://doi.org/10.2196/400351439-4456PubMedCentral: PMC9822177ORCID: /0000-0003-2606-2405/work/145602488https://hdl.handle.net/2164/22017This work uses data provided by patients and collected by the National Health Service as part of their care and support. We acknowledge the support from CO-CONNECT funded by United Kingdom Research and Innovation (Medical Research Council) and the Department of Health and Social Care (National Institute of Health and Care Research) (MR/V03488X/1) and supported by a consortium of 22 partner organizations whose infrastructure made this research possible. The work builds on early pilot work supported by the University of Nottingham Impact Acceleration Account (EP/R511730/1) from the Engineering and Physical Sciences Research Council. This work was supported by Health Data Research UK, which is funded by the UK Medical Research Council, Engineering and Physical Sciences Research Council, Economic and Social Research Council, Department of Health and Social Care (England), Chief Scientist Office of the Scottish Government Health and Social Care Directorates, Health and Social Care Research and Development Division (Welsh Government), Public Health Agency (Northern Ireland), British Heart Foundation and the Wellcome Trust.18897749engSDG 3 - Good Health and Well-beingCOVID-19clinical carepublic healthinfrastructure modelhealth datameta-analysisfederated networkhealth care recorddata extractiondata privacydata governancehealth careR MedicineRA0421 Public health. Hygiene. Preventive MedicineQA75 Electronic computers. Computer scienceMedical Research Council (MRC)MR/V03488X/1Engineering and Physical Sciences Research Council (EPSRC)EP/R511730/1National Institute for Health Research (NIHR)Economic and Social Research Council (ESRC)Chief Scientist Office (CSO)British Heart FoundationWellcome TrustRRA0421QA75A Hybrid Architecture (CO-CONNECT) to Facilitate Rapid Discovery and Access to Data Across the United Kingdom in Response to the COVID-19 Pandemic : Development StudyJournal article10.2196/preprints.40035https://doi.org/10.2196/preprints.400352412