Stolicyn, AleksHarris, Mathew A.Nooij, Laura deShen, XueyiMacfarlane, Jennifer A.Campbell, ArchieMcNeil, Christopher J.Sandu, Anca-LarisaMurray, Alison D.Waiter, Gordon D.Lawrie, Stephen M.Steele, Douglas J.McIntosh, Andrew M.Romaniuk, LianaWhalley, Heather C.2024-06-192024-06-192024-04-15Stolicyn, A, Harris, M A, Nooij, L D, Shen, X, Macfarlane, J A, Campbell, A, McNeil, C J, Sandu, A-L, Murray, A D, Waiter, G D, Lawrie, S M, Steele, D J, McIntosh, A M, Romaniuk, L & Whalley, H C 2024, 'Disrupted Limbic-Prefrontal Effective Connectivity in Response to Fearful Faces in Lifetime Depression', Journal of Affective Disorders, vol. 351, pp. 983-993. https://doi.org/10.1016/j.jad.2024.01.0380165-0327RIS: urn:446E12496915423CBBB9801B9384EA48ORCID: /0000-0002-5555-4129/work/151301838ORCID: /0000-0002-5313-9845/work/151302888https://hdl.handle.net/2164/23655For further details regarding the NimStim dataset of facial expressions please see https://danlab.psychology.columbia.edu/content/nimstim-set-facial-expressions. Development of the MacBrain Face Stimulus Set was overseen by Nim Tottenham and supported by the John D. and Catherine T. MacArthur Foundation Research Network on Early Experience and Brain Development. Please contact Nim Tottenham at nlt7@columbia.edu for more information concerning the stimulus set. The current work has made use of the resources provided by the Edinburgh Compute and Data Facility (ECDF) (http://www.ecdf.ed.ac.uk/). We would like to thank all Generation Scotland research volunteers who took part in the current study for contributing their time and effort. We would also like to thank all research assistants, clinicians and technicians for their valuable contributions to collection of the data.113349210engMajor depressive disorderAmygdalaPrefrontal cortexfearful facesfunctional MRIeffective connectivityR MedicineWellcome Trust104036/Z/14/Z204804/Z/16/Z216767/Z/19/ZMedical Research Council (MRC)MC_PC_17209Chief Scientist Office (CSO)CZD/16/6Scottish Funding CouncilHR03006Supplementary Informationhttps://ars.els-cdn.com/content/image/1-s2.0-S016503272400048X-mmc1.pdfRJournal article10.1016/j.jad.2024.01.038351