Longo, BeatriceZanato, ChiaraPiras, MonicaDall'angelo, SergioWindhorst, Albert D.Vugts, DanielleBaldassarre, MassimilianoZanda, Matteo2021-08-022021-08-022020-09-16Longo, B, Zanato, C, Piras, M, Dall'angelo, S, Windhorst, A D, Vugts, D, Baldassarre, M & Zanda, M 2020, 'Design, synthesis, conjugation and reactivity of novel trans,trans-1,5-cyclooctadiene-derived bioorthogonal linkers', Bioconjugate Chemistry, vol. 31, no. 9, pp. 2201-2210. https://doi.org/10.1021/acs.bioconjchem.0c003751043-1802ORCID: /0000-0002-2498-4767/work/78366843ORCID: /0000-0001-9377-0474/work/176747546https://hdl.handle.net/2164/16896Funding Information: The authors thank Irene Feiner, Marion van Leeuwen-Chomet, and Joey Muns for their helpful insight. We acknowledge financial support from the University of Aberdeen and European Union’s Horizon 2020 research and innovation programme under the Marie Skłodowska-Curie grant agreement no. 675417.10523890engNONCANONICAL AMINO-ACIDSTRANS-CYCLOOCTENECLICK-CHEMISTRYIMPROVED STABILITYALDERANTIBODYPETEFFICIENTDIENOPHILESPROTEINSR Medicine (General)BioengineeringBiotechnologyBiomedical EngineeringPharmacologyPharmaceutical ScienceOrganic ChemistryR1Design, synthesis, conjugation and reactivity of novel trans,trans-1,5-cyclooctadiene-derived bioorthogonal linkersJournal article10.1021/acs.bioconjchem.0c00375http://www.scopus.com/inward/record.url?scp=85091127139&partnerID=8YFLogxK319