Aspden, Richard M.Saunders, Fiona2019-01-302019-01-302019-01-30Aspden, R M & Saunders, F 2019, 'Osteoarthritis as an organ disease : from the cradle to the grave', European Cells & Materials, vol. 37, pp. 74-87. https://doi.org/10.22203/eCM.v037a061473-2262ORCID: /0000-0001-7130-6777/work/54384566http://hdl.handle.net/2164/11845We thank all the members, past and present, of the Orthopaedics Research Group whose work forms our contribution to the quest for a solution to this most disabling disease. We also wish to thank all our surgical colleagues in NHS Grampian who have kindly allowed us to use tissue donated by their patients and provided many stimulating clinical insights. We are grateful to the Medical Research Council, the Arthritis Research Campaign, the Engineering and Physical Sciences Research Council, the Sir Halley Stewart Trust and The Health Foundation for funding research related to this work. We acknowledge grant funding from TMRI Ltd. for some of the SSM studies.14959304engSDG 3 - Good Health and Well-beingosteoarthritisjointsystemic diseasemetabolic diseaseaetiologygrowthhyperplasiadevelopmentGrowthHyperplasiaJointAetiologyMetabolic diseaseSystemic diseaseDevelopmentOsteoarthritisSUBCHONDRAL BONE PLATEFEMORAL-HEADCRUCIATE LIGAMENT INTEGRITYILIAC CREST BONEHIP SHAPESINGLE IMPACT LOADOLIGOMERIC MATRIX PROTEINHUMAN ARTICULAR-CARTILAGEBODY-MASS INDEXKNEE OSTEOARTHRITISR Medicine (General)BioengineeringBiochemistryBiomedical EngineeringCell BiologyBiomaterialsEngineering and Physical Sciences Research Council (EPSRC)Medical Research Council (MRC)R1Journal article10.22203/eCM.v037a06http://www.scopus.com/inward/record.url?scp=85060792551&partnerID=8YFLogxK37