Different intra- and inter-molecular hydrogen-bonding patterns in (3S,4aS,8aS)-2-[(2R,3S)-3-(2,5-X2-benzamido)-2-(2,5-X2-benzo-yloxy)-4-phenyl-butyl]-N-tert-butyldeca-hydro-iso-quinoline-3-carboxamides (X = H or Cl) : compounds with moderate aspartyl protease inhibition activity

Cunico, WilsonFerreira, Maria de Lourdes GWardell, James L.Harrison, William T A2017-06-222017-06-222017-06-01Cunico, W, Ferreira, M D L G, Wardell, J L & Harrison, W T A 2017, 'Different intra- and inter-molecular hydrogen-bonding patterns in (3S,4aS,8aS)-2-[(2R,3S)-3-(2,5-X2-benzamido)-2-(2,5-X2-benzo-yloxy)-4-phenyl-butyl]-N-tert-butyldeca-hydro-iso-quinoline-3-carboxamides (X = H or Cl) : compounds with moderate aspartyl protease inhibition activity', Acta Crystallographica Section E: Crystallographic Communications, vol. 73, no. 6, pp. 913-917. https://doi.org/10.1107/S20569890170078002056-9890Bibtex: urn:62859e863335f5119d6da8f1bfa8f5dfPubMedCentral: PMC5458323http://hdl.handle.net/2164/8850We thank the EPSRC National Crystallography Service (University of Southampton) for the X-ray data collections.5896563engSDG 3 - Good Health and Well-beingcrystal structuremalariaisoquinolinecarboxamidehydrogen bondingaspartyl protease inhibition activityQD ChemistryGeneral ChemistryGeneral Materials ScienceGeneral Physics and AstronomyQDDifferent intra- and inter-molecular hydrogen-bonding patterns in (3S,4aS,8aS)-2-[(2R,3S)-3-(2,5-X2-benzamido)-2-(2,5-X2-benzo-yloxy)-4-phenyl-butyl]-N-tert-butyldeca-hydro-iso-quinoline-3-carboxamides (X = H or Cl) : compounds with moderate aspartyl protease inhibition activityJournal article10.1107/S2056989017007800736