Gonçalves, Samuel M.Duarte-Oliveira, CláudioCampos, Cláudia F.Aimanianda, Vishukumarter Horst, RobLeite, LuisMercier, ToinePereira, PauloFernández-García, MiguelAntunes, DanielaRodrigues, Cláudia S.Barbosa-Matos, CatarinaGaifem, JoanaMesquita, InêsMarques, AntónioOsório, Nuno S.Torrado, EgídioRodrigues, FernandoCosta, SandraJoosten, Leo A.B.Lagrou, KatrienMaertens, JohanLacerda, João FCampos Jr, AntónioBrown, Gordon D.Brakhage, Axel ABarbas, CoralSilvestre, Ricardovan de Veerdonk, Frank L.Chamilos, GeorgiosNetea, Mihai G.Latgé, Jean-PaulCunha, CristinaCarvalho, Agostinho2020-06-152020-06-152020Gonçalves, S M, Duarte-Oliveira, C, Campos, C F, Aimanianda, V, ter Horst, R, Leite, L, Mercier, T, Pereira, P, Fernández-García, M, Antunes, D, Rodrigues, C S, Barbosa-Matos, C, Gaifem, J, Mesquita, I, Marques, A, Osório, N S, Torrado, E, Rodrigues, F, Costa, S, Joosten, L A B, Lagrou, K, Maertens, J, Lacerda, J F, Campos Jr, A, Brown, G D, Brakhage, A A, Barbas, C, Silvestre, R, van de Veerdonk, F L, Chamilos, G, Netea, M G, Latgé, J-P, Cunha, C & Carvalho, A 2020, 'Phagosomal removal of fungal melanin reprograms macrophage metabolism to promote antifungal immunity', Nature Communications, vol. 11, 2282. https://doi.org/10.1038/s41467-020-16120-z2041-1723PubMedCentral: PMC7210971https://hdl.handle.net/2164/14501Acknowledgements This work was supported by the Northern Portugal Regional Operational Programme (NORTE 2020), under the Portugal 2020 Partnership Agreement, through the European Regional Development Fund (FEDER) (NORTE-01- 0145-FEDER-000013), the Fundação para a Ciência e Tecnologia (FCT) (SFRH/BD/136814/2018 to S.M.G., SFRH/BD/141127/2018 to C.D.O., PD/BD/137680/2018 to D.A., IF/00474/2014 to N.S.O., IF/01390/2014 to E.T., IF/00959/2014 to S.C., IF/00021/2014 to R.S., PTDC/SAU-SER/29635/2017 and CEECIND/04601/2017 to C.C., and CEECIND/03628/2017 to A.C.), the Institut Mérieux (Mérieux Research Grant 2017 to C.C.), and the European Society of Clinical Microbiology and Infectious Diseases (ESCMID Research Grant 2017 to A.C.). M.G.N. was supported by a Spinoza grant of the Netherlands Organization for Scientific Research. A.A.B. was supported by the Deutsche Forschungsgemeinschaft Collaborative Research Center/Transregio TR124 FungiNet (project A1). G.D.B. was funded by the Wellcome Trust (102705), the MRC Centre for Medical Mycology and the University of Aberdeen (MR/N006364/1).4989992engAspergillusmelaninimmunometabolismglycolysiscalciummacrophageantifungal immunityinvasive pulmonary aspergillosisACTIVATIONASPERGILLUS-FUMIGATUSPHAGOCYTOSISDENDRITIC CELLCONIDIAMTORSUCCINATE-DEHYDROGENASEINHIBITIONBIOSYNTHESISCELLULAR-METABOLISMR Medicine (General)General Physics and AstronomyGeneral ChemistryGeneral Biochemistry,Genetics and Molecular BiologyMedical Research Council (MRC)MR/N006364/1Wellcome Trust102705Supplementary DataR1Journal article10.1038/s41467-020-16120-zhttp://www.scopus.com/inward/record.url?scp=85084721395&partnerID=8YFLogxK11