Gamble, David TRoss, JamesKhan, HilalUnger, AndreasCheyne, LesleyRudd, AmeliaSaunders, FionaSrivanasan, JanakiKamya, SylviaHorgan, GrahamHannah, AndrewBaliga, SantoshTocchetti, Carlo GabrieleUrquhart, GordonLinke, Wolfgang AMasannat, YazanMustafa, AhmedFuller, MairiElsberger, BeatrixSharma, RaviDawson, Dana2023-10-202023-10-202023-10-17Gamble, D T, Ross, J, Khan, H, Unger, A, Cheyne, L, Rudd, A, Saunders, F, Srivanasan, J, Kamya, S, Horgan, G, Hannah, A, Baliga, S, Tocchetti, C G, Urquhart, G, Linke, W A, Masannat, Y, Mustafa, A, Fuller, M, Elsberger, B, Sharma, R & Dawson, D 2023, 'Impaired Cardiac and Skeletal Muscle Energetics Following Anthracycline Therapy for Breast Cancer', Circulation. Cardiovascular imaging, vol. 16, no. 10, e015782, pp. 817-826. https://doi.org/10.1161/CIRCIMAGING.123.0157821941-9651PubMedCentral: PMC10581415ORCID: /0000-0001-7984-6452/work/145113523ORCID: /0000-0003-2815-4469/work/160846718https://hdl.handle.net/2164/21971Acknowledgments The fellow (Dr Gamble) recruited participants, scheduled, coordinated, and performed all clinical imaging investigations, patients skeletal muscle biopsies and venesection, conducted mitochondrial copy number analysis of muscle biopsies under supervision, analyzed all data, performed statistical analyses under supervision, and drafted this article. H. Khan and A. Rudd helped with the investigations and reviewed and contributed to this article. S. Baliga provided the healthy volunteer skeletal muscle biopsies. Dr Ross designed and developed the protocol for cardiac and skeletal muscle spectroscopy. L. Cheyne supervised muscle biopsy analyses. Drs Unger and Linke performed the skeletal muscle transmission electron microscopy and immunofluorescence confocal microscopy investigations. Dr Horgan is the study statistician. Drs Urquhart, Masannat, Elsberger, Fuller, Mustafa, and Sharma identified and recruited participants and reviewed and contributed to this article. Drs Hannah, Sharma, and Saunders contributed to the design of the study. D. Dawson (PI) designed the study, obtained funding (together with Drs Sharma and Masannat) and regulatory approvals, supervised the unfolding of the study, its analyses and revised the article drafts. Sources of Funding Tenovus Scotland G18.01, D. Dawson and Dr Sharma, Friends of Anchor 2019, Grampian National Health Service-Endowments (Drs Sharma and Masannat), British Health Foundation PG/18/35/33786 to D. Dawson funded DG salary and BHF FS/RTF/20/30009 to D. Dawson funded AR salary.10638966engSDG 3 - Good Health and Well-beingR MedicineBritish Heart FoundationPG/18/35/33786FS/RTF/20/30009RJournal article10.1161/CIRCIMAGING.123.0157821610