Soto-Rojas, Luis OCampa-Córdoba, B. BereniceHarrington, CharlesSalas-Casas, AndrésHernandes-Alejandro, MarioVillanueva-Fierro, IgnacioBravo-Muñoz, MarelyGarcés-Ramírez, LindaDe La Cruz-López, FidelOntiveros-Torres, Miguel AngelGevorkian, GoarPacheco-Herrero, MarLuna-Muñoz, José2021-04-012021-04-012021-04-01Soto-Rojas, L O, Campa-Córdoba, B B, Harrington, C, Salas-Casas, A, Hernandes-Alejandro, M, Villanueva-Fierro, I, Bravo-Muñoz, M, Garcés-Ramírez, L, De La Cruz-López, F, Ontiveros-Torres, M A, Gevorkian, G, Pacheco-Herrero, M & Luna-Muñoz, J 2021, 'Insoluble Vascular Amyloid Deposits Trigger Disruption of the Neurovascular Unit in Alzheimer’s Disease Brains', International Journal of Molecular Sciences, vol. 22, no. 7, 3654. https://doi.org/10.3390/ijms220736541422-0067unpaywall: 10.3390/ijms22073654ORCID: /0000-0003-2250-3920/work/173415882https://hdl.handle.net/2164/16167Funding: This work was supported by Fondo Nacional de Ciencia y Tecnologia, FONDOCyT, from the Ministry of Higher Education, Science and Technology, Dominican Republic (2015-3A2-127 to MP-H) and (2018-2019-2A3-208 to J.L.-M. and M.P.-H). Acknowledgments: The authors want to express their gratitude to the following: P. Davies†(Albert Einstein College of Medicine, Bronx, NY, USA) and Lester I. Binder† (North Western, Chicago, IL, USA) for the generous gift of mAbs TG-3 and Alz-50, and Tau-1, Tau-5, and Tau-7, respectively; Tec. Amparo Viramontes Pintos for the handling of the brain tissue; support in the confocal microscopy unit of CIIDIR Durango, Instituto Politécnico Nacional; Union Medica University Clinic, Dominican Republic, for their support and collaboration in the development of this research project. We also want to express our gratitude to the Mexican families who have donated the brain of their loved ones affected by Alzheimer’s disease and made our research possible. This work is dedicated to the memory of José Raúl Mena López† . †Deceased.1859591441engAlzheimer’s diseasefibrillar amyloidpyroglutamate-modified amyloid-beta peptidesneurovascular unitblood–brain barriercaspase-5Caspase-5Neurovascular unitFibrillar amyloidPyroglutamate-modified amyloid-beta peptidesBlood–brain barrierR MedicineMolecular BiologySpectroscopyCatalysisInorganic ChemistryComputer Science ApplicationsPhysical and Theoretical ChemistryOrganic ChemistryRJournal article10.3390/ijms22073654http://www.scopus.com/inward/record.url?scp=85103334888&partnerID=8YFLogxK227