Mihov, MihailShoctor, HannahDouglas, AlexHay, David CO'Shaughnessy, Peter J.Iredale, John PShaw, SophieFowler , Paul Alfred FrançoisGrassmann, Felix2025-05-122025-05-122025-04Mihov, M, Shoctor, H, Douglas, A, Hay, D C, O'Shaughnessy, P J, Iredale, J P, Shaw, S, Fowler , P A F & Grassmann, F 2025, 'Linking epidemiology and genomics of maternal smoking during pregnancy in utero and in ageing : a population-based study using human foetuses and the UK Biobank cohort', EBioMedicine, vol. 114, 1055590. https://doi.org/10.1016/j.ebiom.2025.1055902352-3964ORCID: /0000-0001-6606-1058/work/180268684ORCID: /0000-0002-4831-9075/work/180268796ORCID: /0000-0003-1390-7528/work/189636423https://hdl.handle.net/2164/25393Acknowledgements The current study was conducted under the UK Biobank project 73446. The authors would like to thank (i) the Fowler team members, NHS Grampian research nurses and staff at the Pregnancy Counselling Service for their essential work in recruiting, collecting, and processing foetuses; (ii) the Centre for Genome Enabled Biology and Medicine, University of Aberdeen, for carrying out the RNA sequencing. The RNA sequencing data analysis was supported by use of the University of Aberdeen Maxwell High Performance Computer Cluster.18182670engSubstantive connection via eligible employment contractSDG 3 - Good Health and Well-beingHumansFemalePregnancySmoking/adverse effectsUnited Kingdom/epidemiologyMaleMaternal Exposure/adverse effectsPrenatal Exposure Delayed Effects/epidemiologyBiological Specimen BanksMiddle AgedAdultGenomics/methodsFetus/metabolismAging/geneticsGenome-Wide Association StudyTranscriptomeCohort StudiesUK BiobankR Medicine (General)Supplementary DataDASR1Journal article10.1016/j.ebiom.2025.105590114