Ifrim, Daniela CQuintin, JessicaJoosten, Leo A BJacobs, CorJansen, TreesJacobs, LiesbethGow, Neil A RWilliams, David Lvan der Meer, Jos W MNetea, Mihai G2015-02-042015-02-042014-04Ifrim, D C, Quintin, J, Joosten, L A B, Jacobs, C, Jansen, T, Jacobs, L, Gow, N A R, Williams, D L, van der Meer, J W M & Netea, M G 2014, 'Trained immunity or tolerance : opposing functional programs induced in human monocytes after engagement of various pattern recognition receptors', Clinical and Vaccine Immunology, vol. 21, no. 4, pp. 534-545. https://doi.org/10.1128/CVI.00688-131556-6811http://hdl.handle.net/2164/4235Article Accepted Date: 29 January 2014. ACKNOWLEDGMENTS D.C.I. received funding from the European Union's Seventh Framework Programme (FP7/2007-2013) under grant agreement HEALTH-2010-260338 (“Fungi in the setting of inflammation, allergy and autoimmune diseases: translating basic science into clinical practices” [ALLFUN]) (awarded to M.G.N.). M.G.N. and J.Q. were supported by a Vici grant of the Netherlands Organization of Scientific Research (awarded to M.G.N.). This work was supported, in part, by National Institutes of Health grant GM53522 to D.L.W. N.A.R.G. was supported by the Wellcome Trust.122972095engAntigens, BacterialAntigens, ViralBacteriaCandida albicansCytokinesHumansImmune ToleranceMonocytesReceptors, Pattern RecognitionVirusesQR MicrobiologyWellcome TrustQRJournal article10.1128/CVI.00688-13214