Makin, Stephen DJDoubal, Fergus NQuinn, Terence JBath, Philip MWDennis, Martin SWardlaw, Joanna M2019-09-052019-09-052018Makin, S DJ, Doubal, F N, Quinn, T J, Bath, P MW, Dennis, M S & Wardlaw, J M 2018, 'The effect of different combinations of vascular, dependency and cognitive endpoints on the sample size required to detect a treatment effect in trials of treatments to improve outcome after lacunar and non-lacunar ischaemic stroke', European Stroke Journal , vol. 3, no. 1, pp. 66-73. https://doi.org/10.1177/23969873177288542396-9873RIS: urn:148F9FE0654A9D1C2AE6BF7CEDFCF500RIS: 24391PubMedCentral: 29900411ORCID: /0000-0001-8701-9043/work/76976248http://hdl.handle.net/2164/12856The author(s) disclosed receipt of the following financial support for the research, authorship, and/or publication of this article: The study was funded by the Wellcome Trust (grant 088134/Z/09/A), the Scottish Funding Council and the Chief Scientist Office, Scotland, through the Scottish Imaging Network: A Platform for Scientific Excellence (‘SINAPSE’) and the European Union Horizon 2020 research and innovation programme SVDs@Target under grant agreement 666881. FD and TQ are funded by the Stroke Association/Garfield Weston Foundation and Stroke Association/Chief Scientist Office Senior Lectureships respectively. PMB is Stroke Association Professor of Stroke Medicine and is a NIHR Senior Investigator. The work was supported by the Fondation Leducq Transatlantic Network of Excellence in Small Vessel Disease ref no. 16 CVD 05, and the Horizon 2020 Programme PHC-03-15, project No 666881, ‘SVDs @Target.’ The work was conducted independently of the funders.8311267engStroke cognition dependencylacunar outcomepower calculationrandomised trial sample sizeR MedicineWellcome Trust088134/Z/09/AChief Scientist Office (CSO)Supplementary DataRJournal article10.1177/2396987317728854https://www.ncbi.nlm.nih.gov/pubmed/2990041131