Structural brain correlates of serum and epigenetic markers of inflammation in major depressive disorder

Green, ClaireShen, XueyiStevenson, Anna J.Conole, Eleanor L.S.Harris, Mathew A.Barbu, Miruna C.Hawkins, Emma L.Adams, Mark J.Hillary, Robert F.Lawrie, Stephen M.Evans, Kathryn L.Walker, Rosie M.Morris, Stewart W.Porteous, David J.Wardlaw, Joanna M.Steele, J. DouglasWaiter, Gordon D.Sandu, Anca LarisaCampbell, ArchieMarioni, Riccardo E.Cox, Simon R.Cavanagh, JonathanMcIntosh, Andrew M.Whalley, Heather C.2021-01-122021-01-122021-02-01Green, C, Shen, X, Stevenson, A J, Conole, E L S, Harris, M A, Barbu, M C, Hawkins, E L, Adams, M J, Hillary, R F, Lawrie, S M, Evans, K L, Walker, R M, Morris, S W, Porteous, D J, Wardlaw, J M, Steele, J D, Waiter, G D, Sandu, A L, Campbell, A, Marioni, R E, Cox, S R, Cavanagh, J, McIntosh, A M & Whalley, H C 2021, 'Structural brain correlates of serum and epigenetic markers of inflammation in major depressive disorder', Brain, Behavior, and Immunity, vol. 92, pp. 39-48. https://doi.org/10.1016/j.bbi.2020.11.0240889-1591ORCID: 0000-0002-5313-9845ORCID: 0000-0002-5555-4129ORCID: 0000-0002-0538-4774ORCID: 0000-0002-0435-3562ORCID: 0000-0001-8967-683XORCID: 0000-0002-2595-552XORCID: 0000-0002-7884-5877ORCID: 0000-0003-1249-6106ORCID: 0000-0003-0198-5078ORCID: /0000-0002-5313-9845/work/88320485ORCID: /0000-0002-5555-4129/work/88321105https://hdl.handle.net/2164/15638Acknowledgements The authors thank all of the STRADL and Generation Scotland participants for their time and effort taking part in this study. We would also like to thank all of the research assistants, clinicians and technicians for their help in the collecting this data.101621184engBrain morphologyBrain structureC-reactive proteinCRPDepressionInflammationMajor depressive disorderMethylationMRIWhite matter integrityR MedicineImmunologyEndocrine and Autonomic SystemsBehavioral NeuroscienceScottish Funding CouncilHR03006Wellcome Trust216767/Z/19/Z104036/Z/14/ZMedical Research Council (MRC)MR/R024065/1OtherR01AG054628Supplementary DataRStructural brain correlates of serum and epigenetic markers of inflammation in major depressive disorderJournal article10.1016/j.bbi.2020.11.024http://www.scopus.com/inward/record.url?scp=85097058647&partnerID=8YFLogxK92