An integrative top-down and bottom-up qualitative model construction framework for exploration of biochemical systems

Wu, ZujianPang, WeiCoghill, George M2015-05-112015-05-112015-09Wu, Z, Pang, W & Coghill, G M 2015, 'An integrative top-down and bottom-up qualitative model construction framework for exploration of biochemical systems', Soft Computing, vol. 19, pp. 1595-1610. https://doi.org/10.1007/s00500-014-1467-61432-7643ORCID: /0000-0002-1761-6659/work/59923257ORCID: /0000-0002-2047-8277/work/63561515http://hdl.handle.net/2164/4531The authors would like to thank the support on this research by the CRISP project (Combinatorial Responses In Stress Pathways) funded by the BBSRC (BB/F00513X/1) under the Systems Approaches to Biological Research (SABR) Initiative.161022811engevolution strategysimulated annealingqualitative model learningtop down and bottom-up modellingsystems biologyQA75 Electronic computers. Computer scienceBiotechnology and Biological Sciences Research Council (BBSRC)BB/F00513X/1QA75An integrative top-down and bottom-up qualitative model construction framework for exploration of biochemical systemsJournal article10.1007/s00500-014-1467-619