McClure, JessicaMcIlroy, George DavidSymons, RebeccaClark, SusanCunningham, IainHan, WeipingKania, KarolinaColella, FabioRochford, JustinDe Bari, CosimoRoelofs, Anke2025-01-252025-01-252024-12McClure, J, McIlroy, G D, Symons, R, Clark, S, Cunningham, I, Han, W, Kania, K, Colella, F, Rochford, J, De Bari, C & Roelofs, A 2024, 'Disentangling the detrimental effects of local from systemic adipose tissue dysfunction on articular cartilage in the knee', Osteoarthritis and Cartilage, vol. 32, no. 12, pp. 1552-1565. https://doi.org/10.1016/j.joca.2024.07.0061063-4584ORCID: /0009-0009-4606-9699/work/164967743ORCID: /0000-0003-4230-4355/work/164968283ORCID: /0000-0002-5020-4939/work/164968482ORCID: /0009-0002-2404-5847/work/171980072https://hdl.handle.net/2164/24937The authors thank all members and research project students of the Arthritis and Regenerative Medicine Laboratory at the University of Aberdeen. The authors are also grateful to Animal Facility staff for care of our animals, and staff in the Microscopy and Histology Facility and the qPCR Facility for their expert support. Part of this work has been previously presented at OARSI 2022 World Congress: J.J. McClure, G.D. McIlroy., F. Colella, R.A. Symons, S.M. Clark, J.J. Rochford, C. De Bari, A.J. Roelofs. Decreased intra-articular adipose tissue in the knee joint does not affect osteoarthritis development in mice. Osteoarthr Cartil 2022;30:S334.1414309655engSubstantive connection via an eligible employment contractSDG 3 - Good Health and Well-beingOsteoarthritisobesityinfrapatellar fat padarticular cartilagelipodystrophyR MedicineSupplementary Informationhttps://ars.els-cdn.com/content/image/1-s2.0-S1063458424013128-mmc1.pdfRJournal article10.1016/j.joca.2024.07.0063212