Muir, Keith WFord, Gary AFord, IanWardlaw, Joanna MMcConnachie, AlexGreenlaw, NicolaMair, GrantSprigg, NikolaPrice, Christopher IMacLeod, Mary JoanDima, SofiaVenter, MariusZhang, LiqunO’Brien, EoinSanyal, RanjanReid, JohnSztriha, Laszlo KHaider, SyedWhiteley, William NKennedy, JamesPerry, RichardLakshmanan, SekaranChakrabarti, AnnieHassan, AhamadMarigold, RichardRaghunathan, SenthilSims, DonBhandari, MohitWiggam, IvanRashed, KhalidDouglass, ChrisATTEST-2 Investigators2024-10-182024-10-182024-11-30Muir, K W, Ford, G A, Ford, I, Wardlaw, J M, McConnachie, A, Greenlaw, N, Mair, G, Sprigg, N, Price, C I, MacLeod, M J, Dima, S, Venter, M, Zhang, L, O’Brien, E, Sanyal, R, Reid, J, Sztriha, L K, Haider, S, Whiteley, W N, Kennedy, J, Perry, R, Lakshmanan, S, Chakrabarti, A, Hassan, A, Marigold, R, Raghunathan, S, Sims, D, Bhandari, M, Wiggam, I, Rashed, K, Douglass, C & ATTEST-2 Investigators 2024, 'Tenecteplase versus alteplase for acute stroke within 4·5 h of onset (ATTEST-2) : a randomised, parallel group, open-label trial', The Lancet neurology, vol. 23, no. 11, pp. 1087-1096. https://doi.org/10.1016/S1474-4422(24)00377-61474-4422Bibtex: MUIR20241087ORCID: /0000-0003-2115-8184/work/170010490https://hdl.handle.net/2164/24433Acknowledgments The trial was funded by the Stroke Association and British Heart Foundation (grant reference numbers TSA BHF 2015/01 and CS/15/8/32065). Tenecteplase was supplied free of charge by Boehringer Ingelheim. We thank the following individuals: on the Independent Data Monitoring Committee: Richard Lindley (Chair), Graeme MacLennan, and Charlotte Cordonnier. We acknowledge the contributions of key trial support team members: Shirley Mitchell (trial management); Mairi Warren (project and trial management); Alicia Murray (trial management); Angela Welch, Wilma Smith, Emma MacRae, and Wendy Jackson (central outcome assessment); Kirsty Wetherall (statistical checking); John McHugh (database manager); Jane Aziz, Christopher Graham, and Robbie Wilson (electronic data capture and randomisation systems development); Eleni Sakka (imaging database management); Jeb Palmer (University of Edinburgh Systematic Image Review Service oversight); David Perry and David Buchanan (scan housekeeping system); and Lesley Cala, Daisy Mollison, and Elena Boyd (scan reading).10650946engSubstantive connection via an eligible employment contractR MedicineOtherCS/15/8/32065TSA BHF 2015/01Supplementary DataRJournal article10.1016/S1474-4422(24)00377-62311