Usmani, Omar SKemppinen, AnuGardener, ElizabethThomas, VickyKonduru, Priyanka RajuCallan, ChristinaMcLoughlin, AndrewWoodhead, VanessaBrady, AdamJuniper, Elizabeth FBarnes, Peter JPrice, David2018-03-262018-03-262017-09Usmani, O S, Kemppinen, A, Gardener, E, Thomas, V, Konduru, P R, Callan, C, McLoughlin, A, Woodhead, V, Brady, A, Juniper, E F, Barnes, P J & Price, D 2017, 'A Randomized Pragmatic Trial of Changing to and Stepping Down Fluticasone/Formoterol in Asthma', The journal of allergy and clinical immunology. In practice, vol. 5, no. 5, pp. 1378-1387.e5. https://doi.org/10.1016/j.jaip.2017.02.0062213-2201http://hdl.handle.net/2164/10241Acknowledgements We thank the study participants and the principal investigators and staff at the study sites for their contributions (listed in Table E7 in this article's Online Repository at www.jaci-inpractice.org). We are grateful to Optimum Patient Care Ltd research nurses Latife Hardaker, Miriam Cottle, Susanne Skinner, and Amanda Rosenberg and to Interface Clinical Services for site and patient recruitment and conduct of study clinics. We thank the Research in Real Life Ltd study team members Marjan Bojarnejad, Elwira Fidziukiewicz, Clare Fraser, Tahreem Sarwar, Cate Savage, and Natalie Tett for their support in the setup and conduct of the study and Clinical Studies lead Sandra Kreuzaler for study oversight. We also thank Alessandra Cifra for support with medical writing. MedDRA is owned by the International Federation of Pharmaceutical Manufacturers & Associations (IFPMA) on behalf of the International Council for Harmonisation of Technical Requirements for Pharmaceuticals for Human Use (ICH).1087781engACQ7BiomarkersCombination therapyFluticasoneFormoterolFractional exhaled nitric oxideInhaled corticosteroidsPragmatic trialsSalmeterolStep-downAntiasthmatic agentsR MedicineGeneral MedicineRJournal article10.1016/j.jaip.2017.02.00655