Burke, Luke K.Doslikova, BarboraD'Agostino, GiuseppeGreenwald-Yarnell, MeganGeorgescu, TeodoraChianese, RaffaellaMartinez de Morentin, Pablo B.Ogunnowo-Bada, EmmanuelCansell, CelineValencia-Torres, LourdesGarfield, Alastair S.Apergis-Schoute, JohnLam, Daniel D.Speakman, John R.Rubinstein, MarceloLow, Malcolm J.Rochford, Justin J.Myers, Martin G.Evans, Mark L.Heisler, Lora K.2016-03-182016-03-182016-03Burke, L K, Doslikova, B, D'Agostino, G, Greenwald-Yarnell, M, Georgescu, T, Chianese, R, Martinez de Morentin, P B, Ogunnowo-Bada, E, Cansell, C, Valencia-Torres, L, Garfield, A S, Apergis-Schoute, J, Lam, D D, Speakman, J R, Rubinstein, M, Low, M J, Rochford, J J, Myers, M G, Evans, M L & Heisler, L K 2016, 'Sex difference in physical activity, energy expenditure and obesity driven by a subpopulation of hypothalamic POMC neurons', Molecular Metabolism, vol. 5, no. 3, pp. 245-252. https://doi.org/10.1016/j.molmet.2016.01.0052212-8778ORCID: /0000-0002-5020-4939/work/53729085http://hdl.handle.net/2164/5703Acknowledgments Work was supported by the Wellcome Trust (WT098012; WT081713) and Biotechnology and Biological Sciences Research Council (BB/K001418/1) to LKH, Wellcome Trust (093566/Z/10/A) to LKB/LKH, the Diabetes UK (13/0004680) to MLE, the Genomics/Transcriptomics core, Disease Model Core, Bespoke Mouse Models, Imaging, Proteomics Wellcome Trust Strategic Award [100574/Z/12/Z] and Genomics/Transcriptomics Core Facilities, Disease Model Core, CBAL MRC Metabolic Diseases Unit [MRC_MC_UU_12012/5] to LKH, MLE, BD and LKB, the Neuroscience Graduate Program, University of Michigan to MG-Y, the National Institute of Health (DK066604) to MJL and (DK068400) to MJL and MR, and National Institute of Health (DK056731) and the Marilyn H. Vincent Foundation to MGM. The University of Michigan Transgenic Core facility is partially supported by the NIH-funded University of Michigan Center for Gastrointestinal Research (DK034933). The authors would like to thank Dr Samuel Virtue for technical training in BAT lipid accumulation quantification.81797269engSDG 3 - Good Health and Well-being5-HT2c receptorBrown adipose tissueEnergy expenditureHyperinsulinemiaHypothalamusObesityPro-opiomelanocortin (Pomc)Sexual dimorphismR MedicineQH301 BiologyCell BiologyMolecular BiologyWellcome TrustWT098012WT081713093566/Z/10/A100574/Z/12/ZBiotechnology and Biological Sciences Research Council (BBSRC)BB/K001418/1Medical Research Council (MRC)MRC_MC_UU_12012/5RQH301Journal article10.1016/j.molmet.2016.01.005http://www.scopus.com/inward/record.url?scp=84959140900&partnerID=8YFLogxK53