Smid, Dionne E.Franssen, Frits M.E.Gonik, MariaMiravitlles, MarcCasanova, CiroCosio, Borja G.de Lucas-Ramos, PilarMarin, Jose M.Martinez, CristinaMir, IsabelSoriano, Joan B.de Torres, Juan P.Agusti, AlvarAtalay, Nart B.Billington, JuliaBoutou, Afroditi K.Brighenti-Zogg, StefanieChaplin, EmmaCoster, SamanthaDodd, James W.Dürr, SelinaFernandez-Villar, AlbertoGroenen, Miriam T.J.Guimarães, MiguelHejduk, KarelHiggins, VictoriaHopkinson, Nicholas S.Horita, NobuyukiHouben-Wilke, SarahJanssen, Daisy J.A.Jehn, MelissaJoerres, RudolfKarch, AnnikaKelly, Julia L.Kim, Yu-IlKimura, HiroshiKoblizek, VladimirKocks, Janwillem H.Kon, Samantha S.C.Kwon, NamheeLadeira, InêsLee, Sang-DoLeuppi, Joerg D.Locantore, NicholasLopez-Campos, José L.D-C Man, WilliamMaricic, LanaMendoza, LauraMiedinger, DavidMihaltan, FlorinMinami, Seigovan der Molen, ThysMurrells, Trevor J.Nakken, NienkeNishijima, YuNorman, Ian J.Novotna, BarboraO'Donnell, Denis E.Ogata, YoshitakaPereira, Eanes D.Piercy, JamesPrice, DavidPothirat, ChaicharnRaghavan, NatyaRingbaek, ThomasSajkov, DimitarSigari, NasehSingh, SallySmall, Markda Silva, Guilherme F.Tanner, Rebecca J.Tsiligianni, Ioanna G.Tulek, BaykalTzanakis, NikolaosVanfleteren, Lowie E.G.W.Watz, HenrikWebb, Katherine A.Wouters, Emiel F.M.Xie, Guogang G.Yoshikawa, MasanoriSpruit, Martijn A.2018-11-202018-11-202017-12-01Smid, D E, Franssen, F M E, Gonik, M, Miravitlles, M, Casanova, C, Cosio, B G, de Lucas-Ramos, P, Marin, J M, Martinez, C, Mir, I, Soriano, J B, de Torres, J P, Agusti, A, Atalay, N B, Billington, J, Boutou, A K, Brighenti-Zogg, S, Chaplin, E, Coster, S, Dodd, J W, Dürr, S, Fernandez-Villar, A, Groenen, M T J, Guimarães, M, Hejduk, K, Higgins, V, Hopkinson, N S, Horita, N, Houben-Wilke, S, Janssen, D J A, Jehn, M, Joerres, R, Karch, A, Kelly, J L, Kim, Y-I, Kimura, H, Koblizek, V, Kocks, J H, Kon, S S C, Kwon, N, Ladeira, I, Lee, S-D, Leuppi, J D, Locantore, N, Lopez-Campos, J L, D-C Man, W, Maricic, L, Mendoza, L, Miedinger, D, Mihaltan, F, Minami, S, van der Molen, T, Murrells, T J, Nakken, N, Nishijima, Y, Norman, I J, Novotna, B, O'Donnell, D E, Ogata, Y, Pereira, E D, Piercy, J, Price, D, Pothirat, C, Raghavan, N, Ringbaek, T, Sajkov, D, Sigari, N, Singh, S, Small, M, da Silva, G F, Tanner, R J, Tsiligianni, I G, Tulek, B, Tzanakis, N, Vanfleteren, L E G W, Watz, H, Webb, K A, Wouters, E F M, Xie, G G, Yoshikawa, M & Spruit, M A 2017, 'Redefining Cut-Points for High Symptom Burden of the Global Initiative for Chronic Obstructive Lung Disease Classification in 18,577 Patients With Chronic Obstructive Pulmonary Disease', Journal of the American Medical Directors Association, vol. 18, no. 12, pp. 1097.e11-1097.e24. https://doi.org/10.1016/j.jamda.2017.09.0031525-8610RIS: urn:163183492D5C7C709429F154A8B0FE03http://hdl.handle.net/2164/11472The authors thank all the patients who participated. In addition, they thank J. Jarkovsky, J. Svancara, and M. Svoboda for their help with data collection and validation within the Czech Multicenter Research Database of Severe COPD. Furthermore, the authors acknowledge Nasrin Moghimi, Shilan Mohammadi, Farhad Sabershahraki, and Daem Roshani for their valuable help during the original study performed in the Tohid Hospital. Subsequently, the authors thank R. Casamor for helping with the On-Sint study.24909537engCOPDGOLDhealth statusclinical significanceR Medicine (General)R1Redefining Cut-Points for High Symptom Burden of the Global Initiative for Chronic Obstructive Lung Disease Classification in 18,577 Patients With Chronic Obstructive Pulmonary DiseaseJournal article10.1016/j.jamda.2017.09.0031812