The Long-term Burden of COPD Exacerbations during Maintenance Therapy and Lung Function Decline

Kerkhof, MarjanVoorham, JacoDorinsky, PaulCabrera, ClaudiaDarken, PatrickKocks, Janwillem W.H.Sadatsafavi, MohsenSin, Don D.Carter, VictoriaPrice, David2020-08-062020-08-062020-08-06Kerkhof, M, Voorham, J, Dorinsky, P, Cabrera, C, Darken, P, Kocks, J W H, Sadatsafavi, M, Sin, D D, Carter, V & Price, D 2020, 'The Long-term Burden of COPD Exacerbations during Maintenance Therapy and Lung Function Decline', International journal of chronic obstructive pulmonary disease , vol. 15, pp. 1909-1918. https://doi.org/10.2147/COPD.S2538121176-9106SCOPUS: 85089812698https://hdl.handle.net/2164/14870Data Sharing Statement The dataset supporting the conclusions of this article was derived from the Clinical Practice Research Datalink (www.cprd.com) and the Optimum Patient Care Research Database (www.opcrd.co.uk). The CPRD has broad National Research Ethics Service Committee (NRES) ethics approval for purely observational research using the primary care data and established data linkages. The OPCRD has ethical approval from the National Health Service (NHS) Research Authority to hold and process anonymized research data (Research Ethics Committee reference: 15/EM/0150). This study was approved by the Anonymized Data Ethics Protocols and Transparency (ADEPT) committee – the independent scientific advisory committee for the OPCRD, and the Independent Scientific Advisory Committee (ISAC) for the CPRD. The authors do not have permission to give public access to the study dataset; researchers may request access to CPRD or OPCRD data for their own purposes. Access to CPRD can be made via the CPRD website (https://www.cprd.com/researcher/) or via the inquiries email enquiries@cprd.com. Access to OCPRD can be made via the OCPRD website (https://opcrd.co.uk/our-database/data-requests/) or via the inquiries email info@opcrd.co.uk. Funding This study is funded by AstraZeneca. AstraZeneca participated in the study design and reporting.1011132509engSDG 3 - Good Health and Well-beingCOPDExacerbationsSpirometryInhalation TherapyObservational Studyinhalation therapyPOPULATIONOBSTRUCTIVE PULMONARY-DISEASEspirometryexacerbationsFREQUENCYobservational studyObservational studyInhalation therapyR Medicine (General)Public Health, Environmental and Occupational HealthHealth PolicyPulmonary and Respiratory MedicineR1The Long-term Burden of COPD Exacerbations during Maintenance Therapy and Lung Function DeclineJournal article10.2147/COPD.S253812http://www.scopus.com/inward/record.url?scp=85089812698&partnerID=8YFLogxK15