A novel, essential trans-splicing protein connects the nematode SL1 snRNP to the CBC-ARS2 complex

Fasimoye, Rotimi YemiSpencer, Rosie ElizabethSoto Martin, EvaEijlers, PeterElmassoudi, HaitemBrivio, SarahMangana, CarolinaSabele, ViktorijaRechtorikova, RadoslavaWenzel, MariusConnolly, BernadettePettitt, JonathanMüller, Berndt Marino2022-09-272022-09-272022-07-22Fasimoye, R Y, Spencer, R E, Soto Martin, E, Eijlers, P, Elmassoudi, H, Brivio, S, Mangana, C, Sabele, V, Rechtorikova, R, Wenzel, M, Connolly, B, Pettitt, J & Müller, B M 2022, 'A novel, essential trans-splicing protein connects the nematode SL1 snRNP to the CBC-ARS2 complex', Nucleic Acids Research, vol. 50, no. 13, pp. 7591-7607. https://doi.org/10.1093/nar/gkac5340305-1048ORCID: /0000-0003-1279-5421/work/115134754ORCID: /0000-0003-0093-368X/work/115134662ORCID: /0000-0001-8195-7880/work/115134931ORCID: /0000-0001-7988-6833/work/160389557ORCID: /0009-0009-3364-1174/work/188340733ORCID: /0000-0003-1279-5421/work/115134754https://hdl.handle.net/2164/19232Open Access via the OUP Agreement Some strains were provided by the Caenorhabditis Genetics Center, which is funded by NIH Office of Research Infrastructure Programs (P40 OD010440). Sequencing was performed by the Centre for Genome-Enabled Biology and Medicine of the University of Aberdeen, and proteomics analysis by the University of Aberdeen Proteomics facility. We thank WormBase for providing the community resource that facilitated the interrogation of C. elegans molecular genetics used in this work. FUNDING Biotechnology and Biological Sciences Research Council [BB/T002859/1]; EASTBIO Biotechnology and Biological Sciences Research Council PhD Studentship [BB/M010996/1 to R.E.B.S.]; University of Aberdeen Elphinstone PhD studentship (to R.Y.F.); University of Aberdeen. Funding for open access charge: Read and publish Agreement Scottish Institutions (SHEDL affiliated).175876175engR MedicineBiotechnology and Biological Sciences Research Council (BBSRC)BB/T002859/1BB/M010996/1Supplementary DataRA novel, essential trans-splicing protein connects the nematode SL1 snRNP to the CBC-ARS2 complexJournal article10.1093/nar/gkac534https://abdn.elsevierpure.com/en/publications/2cee4001-b246-4b07-8fc5-8c910fe6ca1d5013