Fleming, MichaelFitton, Catherine ASteiner, Markus F CMcLay, James SClark, DavidKing, AlbertMackay, Daniel FPell, Jill P2020-03-062020-03-062020-08Fleming, M, Fitton, C A, Steiner, M F C, McLay, J S, Clark, D, King, A, Mackay, D F & Pell, J P 2020, 'Educational and health outcomes of children and adolescents receiving antidepressant medication : Scotland-wide retrospective record linkage cohort study of 766 237 schoolchildren', International Journal of Epidemiology, vol. 49, no. 4, dyaa002, pp. 1380-1391. https://doi.org/10.1093/ije/dyaa0020300-5771https://hdl.handle.net/2164/13830Funding Health Data Research UK (grant reference number MR/S003800/1). Acknowledgements The study was sponsored by Health Data Research UK (www.hdruk.ac.uk), which is a joint investment led by the Medical Research Council, together with the National Institute for Health Research (England), the Chief Scientist Office (Scotland), Health and Care Research Wales, Health and Social Care Research and Development Division (Public Health Agency, Northern Ireland), the Engineering and Physical Sciences Research Council, the Economic and Social Research Council, the British Heart Foundation and Wellcome (grant reference number MR/S003800/1). The sponsor and funders had no role in the design and conduct of the study; collection, management, analysis and interpretation of the data; preparation, review or approval of the manuscript; or decision to submit the manuscript for publication. This study formed part of a wider PhD thesis undertaken by the lead author within the University of Glasgow and was published in 2017. Certain sections of this paper appear in the thesis, which is accessible and downloadable from the following link: http://theses.gla.ac.uk/8594/1/2017flemingphd.pdf. Author Contributions J.P.P. had the original concept. All authors agreed the study design. D.C. and A.K. provided data and undertook record linkage. M.F. and D.F.M. undertook the statistical analyses. All authors interpreted the results. M.F. and J.P.P. drafted the manuscript and all other authors contributed revisions. All authors reviewed and approved the final version of the manuscript. M.F. is guarantor for the study. Approvals The authors applied for permission to access, link and analyse these data and undertook mandatory training in data protection, IT security and information governance. Therefore, the datasets generated and analysed during the study are not publicly available. The study was approved by the National Health Service Privacy Advisory Committee and covered by a data-processing agreement between Glasgow University and ISD, and a data-sharing agreement between Glasgow University and ScotXed. All data were linked by the Electronic Data Research and Innovation Service (eDRIS), part of NHS National Services Scotland. Ethics The NHS West of Scotland Research Ethics Service confirmed that formal NHS ethics approval was not required, since the study involved anonymized extracts of routinely collected data with an acceptably negligible risk of identification. Conflict of interest: None declared12467317engDepressioneducational outcomeshealthpopulation cohortrecord linkageprescribingEducational outcomesPopulation cohortPrescribingHealthRecord linkageR MedicineEpidemiologyEngineering and Physical Sciences Research Council (EPSRC)Health Data Research UKEconomic and Social Research Council (ESRC)Health Data Research UKMedical Research Council (MRC)Health Data Research UKNational Institute for Health Research (NIHR)Health Data Research UKBritish Heart FoundationHealth Data Research UKWellcome TrustHealth Data Research UKSupplementary DataRJournal article10.1093/ije/dyaa002http://www.scopus.com/inward/record.url?scp=85094148049&partnerID=8YFLogxK494