McIntosh, Andrew MHall, Lynsey SZeng, YanniAdams, Mark JGibson, JudeWigmore, EleanorHagenaars, Saskia PDavies, GailFernandez-Pujals, Ana MariaCampbell, Archie IClarke, Toni-KimHayward, CarolineHaley, Chris SPorteous, David JDeary, Ian JSmith, Daniel JNicholl, Barbara IHinds, David AJones, Amy VScollen, SerenaMeng, WeihuaSmith, Blair HHocking, Lynne J2017-08-292017-08-292016-08-16McIntosh, A M, Hall, L S, Zeng, Y, Adams, M J, Gibson, J, Wigmore, E, Hagenaars, S P, Davies, G, Fernandez-Pujals, A M, Campbell, A I, Clarke, T-K, Hayward, C, Haley, C S, Porteous, D J, Deary, I J, Smith, D J, Nicholl, B I, Hinds, D A, Jones, A V, Scollen, S, Meng, W, Smith, B H & Hocking, L J 2016, 'Genetic and Environmental Risk for Chronic Pain and the Contribution of Risk Variants for Major Depressive Disorder : A Family-Based Mixed-Model Analysis', PLoS Medicine, vol. 13, no. 8, e1002090. https://doi.org/10.1371/journal.pmed.10020901549-1277PubMedCentral: PMC4987025http://hdl.handle.net/2164/9221Funding: This study was funded by Wellcome Trust (www.wellcome.ac.uk) Strategic Grant 104036/Z/14/Z. Generation Scotland (www.gen.acot) is funded by the Chief Scientist Office [CZD/16/6] and the Scottish Funding Council [HR03006]. UK Biobank (www.ukbiobank.ac.uk) is funded by the Wellcome Trust, Medical Research Council, The Scottish Government and other funders. These funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript. The analysis of pain data collected by 23andMe in collaboration with Pfizer and was funded by Pfizer. Employees of Pfizer and 23andMe are represented in the authorship. Data Availability: Data from Generation Scotland are available on application to an independent access committee. The committee can be contacted through the following email (info@generationscotland.org) or web addresses (www.generationscotland.org). Data from UK Biobank are available on application to the UK Biobank Access Committee. The Access Committee may be contacted by email (access@ukbiobank.ac.uk) or through the UK Biobank web page (http://www.ukbiobank.ac.uk). Data from Pfizer-23andMe are available on application to Pfizer. Please apply by email at the following address: HGCBDataAccess@pfizer.com.574008engAdultAgedChronic PainDepressive Disorder, MajorFamilyFemaleGenome-Wide Association StudyHumansMaleMiddle AgedMultifactorial InheritancePedigreeRisk FactorsSocial EnvironmentSurveys and QuestionnairesUnited KingdomJournal ArticleR MedicineWellcome Trust104036/Z/14/ZScottish Funding CouncilHR03006Chief Scientist Office (CSO)CZD/16/6RJournal article10.1371/journal.pmed.1002090138