Sánchez, Jon AndoniAlfonso, AmparoRodriguez, InesAlonso, EvaCifuentes, José ManuelBermudez, RobertoRateb, Mostafa EJaspars, MarcelHoussen, Wael EEbel, RainerTabudravu, JiojiBotana, Luís M2016-11-222016-11-222016-10-24Sánchez, J A, Alfonso, A, Rodriguez, I, Alonso, E, Cifuentes, J M, Bermudez, R, Rateb, M E, Jaspars, M, Houssen, W E, Ebel, R, Tabudravu, J & Botana, L M 2016, 'Spongionella Secondary Metabolites, Promising Modulators of Immune Response through CD147 Receptor Modulation', Frontiers in Immunology, vol. 7, 452. https://doi.org/10.3389/fimmu.2016.004521664-3224PubMedCentral: PMC5075563ORCID: /0000-0002-2426-6028/work/163664426http://hdl.handle.net/2164/7735Acknowledgments The research leading to these results has received funding from the following FEDER cofounded-grants. From CDTI and Technological Funds, supported by Ministerio de Economía y Competitividad, AGL2012-40185-CO2-01, AGL2014-58210-R, and Consellería de Cultura, Educación e Ordenación Universitaria, GRC2013-016, and through Axencia Galega de Innovación, Spain, ITC-20133020 SINTOX. From CDTI under ISIP Programme, Spain, IDI-20130304 APTAFOOD. From the European Union’s Seventh Framework Programme managed by REA – Research Executive Agency (FP7/2007-2013) under grant agreement 312184 PHARMASEA. We wish to thank the Clínica Losada Arránz, especially Ms. Paula López Arránz for providing the human blood samples for T cells purification. JS is supported by a fellowship from Plan Galego de Investigación e Crecemento, Xunta de Galicia, Spain.2526436engSDG 3 - Good Health and Well-beingSDG 14 - Life Below WaterSpongionella sp.CD147cyclophilin AinflammationchemotaxisQR180 ImmunologyQR180Journal article10.3389/fimmu.2016.004527