Evans, AlexanderVanWyk, JillKerr, MargeeCouper, AmyPace, Wilson D.Tarabichi, YasirPullen, RachelPollack, MichaelDrummond, M. BradleyOhar, Jill A.Meldrum, CatherineHan, MeiLan K.Kaplan, AlanWinders, Tonya AWisnivesky, JuanMake, BarryFederman , AlexCarter, VictoriaLang, KatieMapel, DouglasHanania, Nicola A.Stolz, DaianaMartinez , Fernando JPrice, David2025-10-282025-06-23Evans, A, VanWyk, J, Kerr, M, Couper, A, Pace, W D, Tarabichi, Y, Pullen, R, Pollack, M, Drummond, M B, Ohar, J A, Meldrum, C, Han, M K, Kaplan, A, Winders, T A, Wisnivesky, J, Make, B, Federman , A, Carter, V, Lang, K, Mapel, D, Hanania, N A, Stolz, D, Martinez , F J & Price, D 2025, 'Practical Strategies for Achieving System Change in the US : Lessons and Insights from the CONQUEST Quality Improvement Program', Primary Health Care Research and Development, vol. 26, e50. https://doi.org/10.1017/S14634236251001701463-4236https://hdl.handle.net/2164/26318Acknowledgements We wish to acknowledge and thank Steven Cooper, Angelica Tatam, Nicole Yoong, and Matthew Bird of Optimum Patient Care for their contributions to the implementation of CONQUEST in the US. We thank Dr. Norbert Feigler, Senior Medical Director, US Respiratory, at AstraZeneca, for his contributions to the US CONQUEST programme. We thank Hayley Germack of AstraZeneca for critical review of the manuscript. Writing, editorial support, and/or formatting assistance in the development of this manuscript was provided by Shilpa Suresh, MSc, of the Observational and Pragmatic Research Institute, Singapore.12944499engQuality improvementCOPDPrimary careImplementationIntegrated health careR Medicine (General)Supplementary InformationR1Journal article10.1017/S1463423625100170