Vargesson, NeilHootnick, David R.2017-10-202017-10-202017-06-01Vargesson, N & Hootnick, D R 2017, 'Arterial dysgenesis and limb defects : Clinical and experimental examples', Reproductive Toxicology, vol. 70, pp. 21-29. https://doi.org/10.1016/j.reprotox.2016.10.0050890-6238ORCID: /0000-0001-8027-114X/work/145270808http://hdl.handle.net/2164/9482Acknowledgements This article is dedicated to Dr David S. Packard Jr. With thanks to Dr John DeSesso, Dr Lewis B. Holmes, Dr Mark Levinsohn, Dr David S. Packard Jr, Prof Lewis Wolpert for discussions on vascular disruption, particularly arterial dysgenesis and limb defects. We apologise to the many authors whose work we were unable to cite due to space limitations. This research did not receive any specific grant from funding agencies in the public, commercial, or not-for-profit sectors.9560643engSDG 3 - Good Health and Well-beingvascular transitionthalidomideMifepristolvascular disruptionhuman embryovertebrate embryoclubfootvertical talusPFFD (proximal femoral focal deficiency)Holt-oram syndromeR MedicineRJournal article10.1016/j.reprotox.2016.10.00570