Wang, ShanLin, SixingFang, QingGyampoh, RolandLu, ZhouGao, YingliClarke, David JWu, KewenTrembleau, LaurentYu, YiKyeremeh, KwakuMilne, Bruce FTabudravu, JiojiDeng, Hai2022-08-302022-08-302022-08-26Wang, S, Lin, S, Fang, Q, Gyampoh, R, Lu, Z, Gao, Y, Clarke, D J, Wu, K, Trembleau, L, Yu, Y, Kyeremeh, K, Milne, B F, Tabudravu, J & Deng, H 2022, 'A ribosomally synthesised and post-translationally modified peptide containing a β-enamino acid and a macrocyclic motif', Nature Communications, vol. 13, no. 1, 5044. https://doi.org/10.1038/s41467-022-32774-32041-1723ORCID: /0000-0001-6376-9077/work/118192010ORCID: /0000-0002-5522-4808/work/118987600ORCID: /0000-0002-0047-0622/work/159509069https://hdl.handle.net/2164/19120Acknowledgements This work received financial support from Biotechnology and Biological Sciences Research Council UK (S.W. and H.D., BB/P00380X/1 and BB/R00479X/1, D.J.C., BB/R013993/1), Scottish Funding Council Covid-19 Grant extension and Bridging Fund (S.W. and H.D.); UKRI Covid-19 Extension Allocation Fund (S.W. and H.D.); The Elphinstone Scholarship of University of Aberdeen (QF), Leverhulme Trust-Royal Society Africa award (AA090088) and the jointly funded UK Medical Research Council UK Department for International Development (MRC/DFID) Concordat agreement African Research Leaders Award (MR/S00520X/1 to K.K. and H.D.), and National Natural Science Foundation of China (31570033, 31811530299, and 31870035 to Y.Y., 31929001 to H.D.), and the Royal Society-NSFC Newton Mobility Grant Award (IEC\NSFC\170617 to H.D. and Y.Y.). B.F.M. thanks the Portuguese Foundation for Science and Technology for financial support (POCI-01-0145-FEDER-032229 and CENTRO-01-0145-FEDER-000014, 2017-2020). H.D. and S.W. thank Professor Brady Moore in the Scripps Institute of Oceanography, University of San Diego, USA, for the gift of pCAP003 plasmid, Dr. Vladimir Larionov in National Cancer Institute, National Institute of Health, Bethesda, USA for the gift of Sacharomyces cerevisiae VL6-48N strain, Dr Juan-Pablo Gomez-Escribano and Professor Mervyn Bibb in John Innes Centre, UK for the gift of Streptomyces coelicolor M1152, and Samantha Law and Carol Philips in NCIMB Ltd (UK) for the kind gift of Streptomyces kurssanovii NCIMB12788152541797engSDG 3 - Good Health and Well-being2040 Health, Nutrition and WellbeingBiochemistryBiosynthesisNatural productsPeptidesQD ChemistryUK Research and Innovation (UKRI)Biotechnology and Biological Sciences Research Council (BBSRC)BB/P00380X/1BB/R00479X/1BB/R013993/1)OtherAA090088Medical Research Council (MRC)MR/S00520X/1Supplementary DataQDJournal article10.1038/s41467-022-32774-3131