Plucinska, KajaDekeryte, RutaKoss, DavidShearer, KirstyMody, NimeshWhitfield, Phillip D.Doherty, Mary K.Mingarelli, MarcoWelch, AndyRiedel, GernotDelibegovic, MirelaPlatt, Bettina2016-05-302016-05-302016-07Plucinska, K, Dekeryte, R, Koss, D, Shearer, K, Mody, N, Whitfield, P D, Doherty, M K, Mingarelli, M, Welch, A, Riedel, G, Delibegovic, M & Platt, B 2016, 'Neuronal human BACE1 knock-in induces systemic diabetes in mice', Diabetologia, vol. 59, no. 7, pp. 1513-1523. https://doi.org/10.1007/s00125-016-3960-10012-186XORCID: /0000-0002-7852-0749/work/76976921ORCID: /0000-0002-2215-7952/work/147568326ORCID: /0000-0001-6193-3152/work/160847608http://hdl.handle.net/2164/6022Acknowledgements The authors thank S. Tammireddy (Diabetes and Cardiovascular Science, University of the Highlands and Islands, Inverness, UK) for technical support with the lipidomics component. Funding We would like to thank R. Simcox, Romex Oilfield Chemicals, for financial support for KP, and acknowledge additional contributions from the Scottish Alzheimer’s Research UK network for the lipidomics work. The College of Life Science and Medicine, University of Aberdeen, sponsored the imaging study. MD was funded by British Heart Foundation and Diabetes UK; NM was funded by a British Heart Foundation Intermediate Fellowship; KS was funded by a European Foundation for the Study of Diabetes/Lilly programme grant; and RD was funded by an Institute of Medical Sciences PhD studentship.1114856961485696engSDG 3 - Good Health and Well-beingneuronal BACE1glucose homeostasisceramideER stress18FDG-PETinsulin signallingR MedicineBritish Heart FoundationRJournal article10.1007/s00125-016-3960-1597