Mukhopadhya, IndraniMurray, Graeme I.Berry, SusanThomson, JohnFrank, BruceGwozdz, GarryEkeruche-Makinde, JuliaShattock, RobinKelly, CharlesIannelli, FrancescoPozzi, GianniEl-Omar, Emad M.Hold, Georgina L.Hijazi, Karolin2017-02-022017-02-022016-02Mukhopadhya, I, Murray, G I, Berry, S, Thomson, J, Frank, B, Gwozdz, G, Ekeruche-Makinde, J, Shattock, R, Kelly, C, Iannelli, F, Pozzi, G, El-Omar, E M, Hold, G L & Hijazi, K 2016, 'Drug Transporter Gene Expression in Human Colorectal Tissue and Cell Lines : Modulation with Antiretrovirals for Microbicide Optimization', Journal of Antimicrobial Chemotherapy, vol. 71, no. 2, pp. 372-386. https://doi.org/10.1093/jac/dkv3350305-7453ORCID: /0000-0002-8589-2129/work/59177123ORCID: /0000-0003-3981-2420/work/76973579ORCID: /0000-0003-2577-518X/work/102536928http://hdl.handle.net/2164/8110Funding This work was supported by the European Union's Seventh Framework Programme for research, technological development and demonstration under grant agreement No 305316 as part of the MOTIF (Microbicide Optimization Through Innovative Formulation for Vaginal and Rectal Delivery) project. Acknowledgements We thank members of the MOTIF consortium for useful discussions and exchange of ideas during the course of this study. We would like to extend our thanks to the study participants and the clinical teams for their invaluable contribution. We thank NHS Grampian Biorepository for support in performing the immunohistochemical studies, Janssen R&D Ireland for provision of darunavir and Gilead Sciences for provision of tenofovir.159678607engSDG 3 - Good Health and Well-beingR MedicineRJournal article10.1093/jac/dkv335712