Invasive urodynamic investigations in the management of women with refractory overactive bladder symptoms (FUTURE) in the UK : a multicentre, superiority, parallel, open-label, randomised controlled trial

Abdel-Fattah, MohamedChapple, ChristopherCooper, DavidBreeman, SuzanneBell-Gorrod, HelenKuppanda, PrekshaGuerrero, Karen L.Dixon, SimonCotterill, NikkiWard, KarenHashim, HashimMonga, AshBrown, KarenDrake, Marcus JGammie, AndrewMostafa, AlyaaBruce, RebeccaBell, VictoriaKennedy, ChristineEvans, SuzanneMacLennan, GraemeNorrie, JohnFUTURE Study Group2025-06-132025-06-132025-03-29Abdel-Fattah, M, Chapple, C, Cooper, D, Breeman, S, Bell-Gorrod, H, Kuppanda, P, Guerrero, K L, Dixon, S, Cotterill, N, Ward, K, Hashim, H, Monga, A, Brown, K, Drake, M J, Gammie, A, Mostafa, A, Bruce, R, Bell, V, Kennedy, C, Evans, S, MacLennan, G, Norrie, J & FUTURE Study Group 2025, 'Invasive urodynamic investigations in the management of women with refractory overactive bladder symptoms (FUTURE) in the UK : a multicentre, superiority, parallel, open-label, randomised controlled trial', The Lancet, vol. 405, no. 10484, pp. 1057-1068. https://doi.org/10.1016/S0140-6736(24)01886-50140-6736ORCID: /0000-0002-1039-5646/work/180763610https://hdl.handle.net/2164/25567Open Access via the Elsevier agreement We thank all the women who participated in the FUTURE trial. We also thank members of the CHaRT team for their support throughout the study; Abualbishr Alshreef who contributed to the economic data collection and analysis and Praveen Thokala for the modelling and value for information analysis; Megan Pardoe who contributed to the qualitative component until December, 2021; members of the Project Management Group for their ongoing advice and support, the independent members of the Trial Steering Committee (Trish Emerson, Barbara Farrell, Malcolm Lucas [Chair from December, 2018], Sanjeev Prashar, and Christopher Mayne (Chair until December, 2018]), the Data Monitoring Committee (Steve Payne [Chair], Lee Middleton, and Dudley Robinson), and the staff at the recruitment sites who facilitated the recruitment, treatment, and follow-up of trial participants (all listed in the FUTURE Study Group section).12795337engSDG 3 - Good Health and Well-beingR Medicine (General)Supplementary DataDASSupplementary InformationR1Invasive urodynamic investigations in the management of women with refractory overactive bladder symptoms (FUTURE) in the UK : a multicentre, superiority, parallel, open-label, randomised controlled trialJournal article10.1016/S0140-6736(24)01886-540510484