Diamantopoulou, ZoiWhite, GavinFadlullah, Muhammad Z HDreger, MarcelPickering, KarenMaltas, JoeAshton, GarryMacLeod, RuthBaillie, George S.Kouskoff, ValerieLacaud, GeorgesMurray, Graeme ISansom, Owen J.Hurlstone, Adam F.L.Malliri, Angeliki2017-05-182017-05-182017-05-08Diamantopoulou, Z, White, G, Fadlullah, M Z H, Dreger, M, Pickering, K, Maltas, J, Ashton, G, MacLeod, R, Baillie, G S, Kouskoff, V, Lacaud, G, Murray, G I, Sansom, O J, Hurlstone, A F L & Malliri, A 2017, 'TIAM1 Antagonizes TAZ/YAP Both in the Destruction Complex in the Cytoplasm and in the Nucleus to Inhibit Invasion of Intestinal Epithelial Cells', Cancer Cell, vol. 31, no. 5, pp. 621-634.e6. https://doi.org/10.1016/j.ccell.2017.03.0071535-6108ORCID: /0000-0003-3981-2420/work/76973593http://hdl.handle.net/2164/8649This work was supported by MRC (grant number MR/L007495/1) and Cancer Research UK (grant number C5759/A12328) to A.M. We thank members of the Cell Signalling Group for helpful discussions and critical reading of the manuscript. We also thank the Molecular Biology Core Facility of CRUK Manchester Institute (CRUK MI) for performing next generation sequencing as well as the CRUK MI Computational Biology Group for preliminary bioinformatics analysis.218671895engSDG 3 - Good Health and Well-beingTIAM1TAZYAPWNTintestinal tumorigenesiscolorectal cancercell migrationinvasionmalignant progressionRC0254 Neoplasms. Tumors. Oncology (including Cancer)Medical Research Council (MRC)MR/L007495/1Cancer Research UKC5759/A12328Supplementary DataRC0254TIAM1 Antagonizes TAZ/YAP Both in the Destruction Complex in the Cytoplasm and in the Nucleus to Inhibit Invasion of Intestinal Epithelial CellsJournal article10.1016/j.ccell.2017.03.007315