Blencowe, Natalie SBrown, Julia MCook, Jonathan AMetcalfe, ChrisMorton, Dion GNicholl, JonSharples, Linda DTreweek, ShaunBlazeby, Jane MMembers of the MRC Hub for Trials Methodology Research Network Workshop2015-11-022015-11-022015-09-04Blencowe, N S, Brown, J M, Cook, J A, Metcalfe, C, Morton, D G, Nicholl, J, Sharples, L D, Treweek, S, Blazeby, J M & Members of the MRC Hub for Trials Methodology Research Network Workshop 2015, 'Interventions in randomised controlled trials in surgery : issues to consider during trial design', Trials, vol. 16, 392. https://doi.org/10.1186/s13063-015-0918-41745-6215ORCID: /0000-0002-7239-7241/work/186968597http://hdl.handle.net/2164/5151Acknowledgements This work was supported by the MRC Network of Hubs for Trials Methodology Research (MR/L004933/1-R/N29), the MRC ConDuCT Hub (Collaboration and innovation for Difficult and Complex randomized controlled Trials In Invasive procedures - MR/K025643/1) and the MRC Biostatistics Hub (Cambridge). NSB is an NIHR Academic Clinical Lecturer. This paper presents independent research funded by the National Institute for Health Research (NIHR). The views expressed are those of the author(s) and not necessarily those of the NHS, the NIHR or the Department of Health. JAC holds a Medical Research Council UK Methodology fellowship (G1002292). The Health Services Research Unit at the University of Aberdeen is funded by the Chief Scientist Office of the Scottish Government Health Directorates.9478193engsurgical trialstrial designcomplex interventionsmethodologystandardisationadherence/fidelityexpertiseR MedicineRJournal article10.1186/s13063-015-0918-416